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A 26-year-old male patient with elevated serum parathyroid hormones and calcium secondary to intra-thyroid parathyroid adenoma. a, b Enhanced axial and coronal CT scan of the neck demonstrate a well-defined hypodense right thyroid nodule (white arrows). c Bone window coronal CT scan shows lytic expansile lesions at the right mandible and left ...
An autonomous thyroid nodule or "hot nodule" is one that has thyroid function independent of the homeostatic control of the HPT axis (hypothalamic–pituitary–thyroid axis). According to a 1993 article, such nodules need to be treated only if they become toxic; surgical excision (thyroidectomy), radioiodine therapy, or both may be used. [33]
A cold nodule is a thyroid nodule that does not produce thyroid hormone. [1] On a radioactive iodine uptake test a cold nodule takes up less radioactive material than the surrounding thyroid tissue. [1] A cold nodule may be malignant or benign. [1] On scintigraphy cold nodules do not show but are easily shown on ultrasound. [2]
Treatment of a thyroid nodule depends on many things including size of the nodule, age of the patient, the type of thyroid cancer, and whether or not it has spread to other tissues in the body. If the nodule is benign, patients may receive thyroxine therapy to suppress thyroid-stimulating hormone and should be reevaluated in six months. [2]
Thyroid follicular adenoma ranges in diameter from 3 cm on an average, but sometimes is larger (up to 10 cm) or smaller. The typical thyroid adenoma is solitary, spherical and encapsulated lesion that is well demarcated from the surrounding parenchyma. The color ranges from gray-white to red-brown, depending upon the cellularity of the adenoma
An ARFI image of a thyroid nodule in the right thyroid lobe. The shear wave speed inside the box is 6.24 m/s, which is reflective of a high stiffness. Histology revealed papillary carcinoma. Acoustic radiation force impulse imaging (ARFI) [5] uses ultrasound to create a qualitative 2-D map of tissue stiffness.
An incidentally found nodule in the absence of symptoms (sometimes referred to as an incidentaloma) may raise concerns that it might represent a tumor, either benign or malignant. [45] Perhaps persuaded by fear, patients and doctors sometimes agree to an intensive schedule of CT scans, sometimes up to every three months and beyond the ...
Papillary thyroid cancer (magnified at right) arising within ectopic thyroid tissue of a thyroglossal cyst is a rare occurrence (less than 1% of such cysts). [38] According to Surveillance, Epidemiology, and End Results (SEER), the incidence of papillary cancer has increased from 4.8 to 14.9 per 100,000 from 1975 to 2012. Females are more ...