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Gastroesophageal reflux disease (GERD) or gastro-oesophageal reflux disease (GORD) is a chronic upper gastrointestinal disease in which stomach content persistently and regularly flows up into the esophagus, resulting in symptoms and/or complications.
There are several classes of drugs for acid-related disorders, such as dyspepsia, peptic ulcer disease (PUD), gastroesophageal reflux disease (GORD/GERD), or laryngopharyngeal reflux. The World Health Organization gives drugs in these classes the categorization code ATC code A02.
Symptoms may include upper abdominal fullness, heartburn, nausea, belching, or upper abdominal pain. [3] People may also experience feeling full earlier than expected when eating. [4] Indigestion is relatively common, affecting 20% of people at some point during their life, and is frequently caused by gastroesophageal reflux disease (GERD) or ...
A history of heartburn or gastroesophageal reflux disease (GERD) and use of certain medications can raise the suspicion for peptic ulcer. Medicines associated with peptic ulcer include NSAIDs (non-steroidal anti-inflammatory drugs) that inhibit cyclooxygenase and most glucocorticoids (e.g., dexamethasone and prednisolone ).
A typical adult human stomach will secrete about 1.5 liters of gastric juice daily. [3] Gastric juice is the combination of gastric gland secretions including the main component of hydrochloric acid (gastric acid), gastric lipase and pepsinogen. [4]
The incidence of acid reflux disease, Barrett's esophagus, and esophageal cancer have been rising dramatically at the same time as H. pylori ' s presence decreases. [185] In 1996, Martin J. Blaser advanced the hypothesis that H. pylori has a beneficial effect by regulating the acidity of the stomach contents.
Gerd or GERD may refer to: Gerd (given name), a list of people with the given name or nickname; Gerd (moon), a moon of Saturn; Gerd Island, South Orkney Islands, Antarctica; Gastroesophageal reflux disease, a chronic symptom of mucosal damage caused by stomach acid coming up from the stomach into the esophagus
Gastroesophageal reflux (GERD) occurs after pneumatic dilatation in many patients. Pneumatic dilatation is most effective in the long-term on patients over the age of 40; the benefits tend to be shorter-lived in younger patients due to the body's higher rate of recovery from trauma, often resulting in repeat procedures with larger balloons to ...