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  2. Langerhans cell histiocytosis - Wikipedia

    en.wikipedia.org/wiki/Langerhans_cell_histiocytosis

    Langerhans cell histiocytosis (LCH) is an abnormal clonal proliferation of Langerhans cells, abnormal cells deriving from bone marrow and capable of migrating from skin to lymph nodes. Symptoms range from isolated bone lesions to multisystem disease . [ 1 ]

  3. Letterer–Siwe disease - Wikipedia

    en.wikipedia.org/wiki/Letterer–Siwe_disease

    Letterer–Siwe disease, (LSD) or Abt-Letterer-Siwe disease, is one of the four recognized clinical syndromes of Langerhans cell histiocytosis (LCH) and is the most severe form, involving multiple organ systems such as the skin, bone marrow, spleen, liver, and lung. Oral cavity and gastrointestinal involvement may also be seen.

  4. Congenital self-healing reticulohistiocytosis - Wikipedia

    en.wikipedia.org/wiki/Congenital_self-healing...

    Congenital self-healing reticulohistiocytosis is a condition that is a self-limited form of Langerhans cell histiocytosis. [2]: ...

  5. Histiocytosis - Wikipedia

    en.wikipedia.org/wiki/Histiocytosis

    Sinus histiocytosis, a common feature in lymph node biopsies, is characterized by dilated sinuses containing variable numbers of histiocytes. [4] Histiocytosis is a rare disease, thus its diagnosis may be challenging. A variety of tests may be used, including: [5] Imaging CT scans of various organs such as lung, heart and kidneys.

  6. Erdheim–Chester disease - Wikipedia

    en.wikipedia.org/wiki/Erdheim–Chester_disease

    Erdheim–Chester disease (ECD) is an extremely rare disease characterized by the abnormal multiplication of a specific type of white blood cells called histiocytes, or tissue macrophages (technically, this disease is termed a non-Langerhans-cell histiocytosis). It was declared a histiocytic neoplasm by the World Health Organization in 2016. [1]

  7. X-type histiocytosis - Wikipedia

    en.wikipedia.org/wiki/X-type_histiocytosis

    X-type histiocytoses are a clinically well-defined group of cutaneous syndromes characterized by infiltrates of Langerhans cells, as opposed to Non-X histiocytosis in which the infiltrates contain monocytes/macrophages. [1]: 720 Conditions included in this group are: [1]: 720–4 Congenital self-healing reticulohistiocytosis

  8. Chronic multifocal Langerhans cell histiocytosis - Wikipedia

    en.wikipedia.org/wiki/Chronic_multifocal...

    Before the Histiocyte Society classified histiocytoses in the 1980s, the condition was also known as "Histiocytosis X", where "X" denoted the then unknown cause. [9] [10] [11] It is now known as chronic multifocal Langerhans cell histiocytosis, a subtype of LCH. [3] The disease is rare. [12] Most present between the ages of two and six. [2]

  9. Juvenile xanthogranuloma - Wikipedia

    en.wikipedia.org/wiki/Juvenile_xanthogranuloma

    Juvenile xanthogranuloma is a form of histiocytosis, classified as non-Langerhans cell histiocytosis. [1] [2] It is a rare skin disorder that primarily affects children under one year of age but can also be found in older children and adults. [3] It was first described in 1905 by Adamson. [4]