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Horizontal cells span across photoreceptors and summate inputs before synapsing onto photoreceptor cells. [1] [2] Horizontal cells may also synapse onto bipolar cells, but this remains uncertain. [1] [4] There is a greater density of horizontal cells towards the central region of the retina.
Like horizontal cells, amacrine cells work laterally, but whereas horizontal cells are connected to the output of rod and cone cells, amacrine cells affect the output from bipolar cells, and are often more specialized. Each type of amacrine cell releases one or several neurotransmitters where it connects with other cells. [2]
The retina (from Latin rete 'net'; pl. retinae or retinas) is the innermost, light-sensitive layer of tissue of the eye of most vertebrates and some molluscs.The optics of the eye create a focused two-dimensional image of the visual world on the retina, which then processes that image within the retina and sends nerve impulses along the optic nerve to the visual cortex to create visual perception.
In the anatomy of the eye, the inner nuclear layer or layer of inner granules, of the retina, is made up of a number of closely packed cells, of which there are three varieties: bipolar cells, horizontal cells, and amacrine cells.
The horizontal cells introduce lateral inhibition to the dendrites and give rise to the center-surround inhibition which is apparent in retinal receptive fields. The amacrine cells also introduce lateral inhibition to the axon terminal, serving various visual functions including efficient signal transduction with high signal-to-noise ratio. [3]
The human eye is a sensory organ in the visual system that reacts to visible light allowing eyesight. Other functions include maintaining the circadian rhythm, and keeping balance. Arizona Eye Model. "A" is accommodation in diopters. The eye can be considered as a living optical device.
The signal goes first to the bipolar and horizontal cells (yellow layer), then to the amacrine cells and ganglion cells (purple layer), then to the optic nerve fibres. The signals are processed in these layers. First, the signals start as raw outputs of points in the rod and cone cells.
Amacrine II cells are found most densely in the central retina, but are found in the surrounding retinal areas as well. [2] Development. The study of the development of amacrine cells is relatively recent. A recent study found that amacrine cells develop during the Peri-Eye-Opening Period (during 7-28 days post birth).