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  2. Toluene toxicity - Wikipedia

    en.wikipedia.org/wiki/Toluene_toxicity

    The first four seem to be involved in the hydroxylation of toluene to benzyl alcohol. CYP2E1 seems to be the primary enzyme in the hydroxylation of toluene, accounting for roughly 44% of toluene metabolism; [1] however, there is a great deal of ethnic variability, in the Finnish population for example the primary enzyme is CYP2B6.

  3. Toxic encephalopathy - Wikipedia

    en.wikipedia.org/wiki/Toxic_encephalopathy

    Toxic encephalopathy is a neurologic disorder caused by exposure to neurotoxic organic solvents such as toluene, following exposure to heavy metals such as manganese, as a side effect of melarsoprol treatment for African trypanosomiasis, adverse effects to prescription drugs, or exposure to extreme concentrations of any natural toxin such as cyanotoxins found in shellfish or freshwater ...

  4. Halogenation - Wikipedia

    en.wikipedia.org/wiki/Halogenation

    In chemistry, halogenation is a chemical reaction which introduces one or more halogens into a chemical compound. Halide-containing compounds are pervasive, making this type of transformation important, e.g. in the production of polymers, drugs. [1] This kind of conversion is in fact so common that a comprehensive overview is challenging.

  5. Free-radical halogenation - Wikipedia

    en.wikipedia.org/wiki/Free-radical_halogenation

    For example, consider radical bromination of toluene: [5] bromination of toluene with hydrobromic acid and hydrogen peroxide in water. This reaction takes place on water instead of an organic solvent and the bromine is obtained from oxidation of hydrobromic acid with hydrogen peroxide. An incandescent light bulb suffices to radicalize.

  6. File:Toluene Halogenation Reactions V.2.svg - Wikipedia

    en.wikipedia.org/wiki/File:Toluene_Halogenation...

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  7. Toluene - Wikipedia

    en.wikipedia.org/wiki/Toluene

    Toluene is also found in cigarette smoke and car exhaust. If not in contact with air, toluene can remain unchanged in soil or water for a long time. [39] Toluene is a common solvent, e.g. for paints, paint thinners, silicone sealants, [40] many chemical reactants, rubber, printing ink, adhesives (glues), lacquers, leather tanners, and ...

  8. Electrophilic halogenation - Wikipedia

    en.wikipedia.org/wiki/Electrophilic_halogenation

    Halogenation of phenols is faster in polar solvents in a basic environment due to the dissociation of phenol, with phenoxide ions being more susceptible to electrophilic attack as they are more electron-rich. Chlorination of toluene with chlorine without catalyst requires a polar solvent as well such as acetic acid.

  9. Dehalogenation - Wikipedia

    en.wikipedia.org/wiki/Dehalogenation

    In organic chemistry, dehalogenation is a set of chemical reactions that involve the cleavage of carbon-halogen bonds; as such, it is the inverse reaction of halogenation. Dehalogenations come in many varieties, including defluorination (removal of fluorine ), dechlorination (removal of chlorine ), debromination (removal of bromine ), and ...