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An abortive serotonin syndrome state, in which some but not all of the symptoms of the full serotonin syndrome are present, has been reported with venlafaxine at mid-range dosages (150 mg per day). [46] A case of a patient with serotonin syndrome induced by low-dose venlafaxine (37.5 mg per day) has also been reported. [47]
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SH-834 was a combination of 90 mg estradiol valerate and 300 mg gestonorone caproate for weekly intramuscular injection that was developed by Schering in the 1970s. [68] [153] [154] It was investigated clinically as a treatment for breast cancer and was found to be effective, but was never marketed. [68] [66]
AMC renewed the series for a 16-episode third season on April 15, 2016. [3] Production began in January 2017 in Baja, Mexico. [4] This was the final season with co-creator Dave Erickson as showrunner as he left the series after the conclusion of the third season. [5]