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Mirtazapine is sometimes described as a noradrenergic and specific serotonergic antidepressant (NaSSA), [11] although the actual evidence in support of this label has been regarded as poor. [17] It is a tetracyclic piperazine-azepine. [85] Mirtazapine has antihistamine, α 2-blocker, and antiserotonergic activity.
The tetracyclic antidepressants mianserin and mirtazapine are α 2 blockers, although their efficacy as antidepressants may come from their activity at other receptor sites. [citation needed] Mechanistically, α 2 blockers increase adrenergic, dopaminergic and serotonergic neurotransmitters and induce insulin secretion, decreasing blood sugar ...
Chemical structure of the prototypical NaSSA mirtazapine (original brand name Remeron). Noradrenergic and specific serotonergic antidepressants (NaSSAs) are a class of psychiatric drugs used primarily as antidepressants. [1]
Functional constipation: This typically happens when kids hold back bowel movements or after they have a gastrointestinal infection. Many children with constipation have functional constipation ...
However, they can also cause constipation or diarrhea, dry mouth, and fatigue. ... Mirtazapine (Remeron) is an antidepressant that also has antiemetic effects. [5] [6
Taking Ozempic can cause nausea, diarrhea, vomiting, and potential muscle loss. Here, doctors share common and uncommon side effects and how to manage them. Ozempic Butt Isn't The Strangest Side ...
Constipation is the most common chronic gastrointestinal disorder in adults. Depending on the definition employed, it occurs in 2% to 20% of the population. [18] [58] It is more common in women, the elderly and children. [58] Specifically constipation with no known cause affects females more often affected than males. [59]
Why the stock market crushed expectations in 2024. Matthew Fox. December 2, 2024 at 9:40 AM. Spencer Platt/Getty Images. The S&P 500 has surged 27% in 2024, on track for its best year since 2019.
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