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Monobromotoluene isomers [1] [2] [3] Common name Structure Systematic name: 1-bromo-2-methylbenzene 1-bromo-3-methylbenzene 1-bromo-4-methylbenzene Molecular formula: C 7 H 7 Br (C 6 H 4 BrCH 3) Molar mass: 171.03 g/mol Appearance colorless liquid colorless liquid white crystalline solid CAS number [95-46-5] [591-17-3]
That is, light can pass into and out of the cleared tissue freely, allowing one to see the structures deep within the tissue without physically cutting it open. Many tissue clearing methods exist, each with different strengths and weaknesses. [2] [4] Some are generally applicable, while others are designed for specific applications. [4]
2-Fluorobenzoic acid is an aromatic organic compound with the formula FC 6 H 4 CO 2 H. It is one of three isomeric fluorobenzoic acids. It is one of three isomeric fluorobenzoic acids. Its conjugate base is 2-fluorobenzoate.
In the first step, two bromine atoms are added to the methyl group of 4-bromotoluene by free radical bromination to form 4-bromobenzal bromide. In the second step, the dibrominated methyl group is hydrolyzed with calcium carbonate , then steam distilled to collect 4-bromobenzaldehyde.
4-Fluorobromobenzene is synthesized via bromination of fluorobenzene in the presence of a Lewis acid catalyst such as iron(III) bromide or aluminium tribromide. [2]4-Bromofluorobenzene is regarded by the Toxic Substances Control Act as a high production volume chemical, that is, a chemical that 1 million pounds (about 500 tonnes) per year is either produced in or imported to the United States.
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Bromoform was discovered in 1832 by Löwig who distilled a mixture of bromal and potassium hydroxide, as analogous to preparation of chloroform from chloral. [5]Bromoform can be prepared by the haloform reaction using acetone and sodium hypobromite, by the electrolysis of potassium bromide in ethanol, or by treating chloroform with aluminium bromide.
6 CH 2 BrCl + 3 Br 2 + 2 Al → 6 CH 2 Br 2 + 2 AlCl 3 CH 2 BrCl + HBr → CH 2 Br 2 + HCl. In the laboratory, it is prepared from bromoform using sodium arsenite and sodium hydroxide: [4] CHBr 3 + Na 3 AsO 3 + NaOH → CH 2 Br 2 + Na 3 AsO 4 + NaBr. Another way is to prepare it from diiodomethane and bromine.