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The formation of phenyl-hydroxy bromazolam was catalysed by CYP2B6, CYP2C19, and CYP3A4. 4-hydroxy bromazolam, as well as α-hydroxy bromazolam, were formed by CYP2B6, CYP2C19, CYP3A4, and CYP3A5. Additionally, CYP2C9 was found to catalyse the formation of α-hydroxy bromazolam as well. α-4-dihydroxy bromazolam was only found in incubations ...
The tables below contain a sample list of benzodiazepines and benzodiazepine analogs that are commonly prescribed, with their basic pharmacological characteristics, such as half-life and equivalent doses to other benzodiazepines, also listed, along with their trade names and primary uses.
Flubromazepam is a benzodiazepine derivative which was first synthesized in 1960, [1] but was never marketed and did not receive any further attention or study until late 2012 when it appeared on the grey market as a novel designer drug.
Flubromazolam (JYI-73) [2] [3] [4] is a triazolobenzodiazepine (TBZD), which are benzodiazepine (BZD) derivatives. [5] [6] [7] [8] [9] [10] [11] Flubromazolam is ...
Bromazepam, sold under many brand names, is a benzodiazepine.It is mainly an anti-anxiety agent with similar side effects to diazepam.In addition to being used to treat anxiety or panic states, bromazepam may be used as a premedicant prior to minor surgery.
Chemical structure of alprazolam, a common triazolobenzodiazepine. Triazolobenzodiazepines (TBZD) are a class of benzodiazepine (BZD) derivative pharmaceutical drugs. . Chemically, they differ from other benzodiazepines by having an additional triazole ring fused to the dia
Felbamate (marketed under the brand name Felbatol by MedPointe) is an anticonvulsant [2] used in the treatment of epilepsy.It is used to treat partial seizures [3] [4] (with and without generalization) in adults and partial and generalized seizures associated with Lennox–Gastaut syndrome in children.
Flubrotizolam (2-bromo-4-(2-fluorophenyl)-9-methyl-6H-thieno[3,2-f][1,2,4]triazolo[4,3-a][1,4]diazepine) is a thienotriazolodiazepine derivative with potent sedative and anxiolytic effects, which has been sold as a designer drug.