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Lean or purple drank (known by numerous local and street names) is a polysubstance drink used as a recreational drug.It is prepared by mixing prescription-grade cough or cold syrup containing an opioid drug and an anti-histamine drug with a soft drink and sometimes hard candy.
Promethazine, sold under the brand name Phenergan among others, is a first-generation antihistamine, sedative, and antiemetic used to treat allergies, insomnia, and nausea. It may also help with some symptoms associated with the common cold [ 4 ] and may also be used for sedating people who are agitated or anxious, an effect that has led to ...
Methylephedrine is a sympathomimetic and ephedrine-like agent. [5] [1] Ephedrine and related agents act as norepinephrine releasing agents and hence as indirectly acting sympathomimetics. [1] In relation to this, methylephedrine stimulates α-and β-adrenergic receptors. [5] [1] The drug has bronchodilator and nasal decongestant effects. [5]
Serious side effects include stroke and heart attack. [11] While probably safe in pregnancy, its use in this population is poorly studied. [12] [13] Use during breastfeeding is not recommended. [13] Ephedrine works by inducing the release of norepinephrine and hence indirectly activating the α-and β-adrenergic receptors. [11]
Effective first generation antihistamines include doxylamine, diphenhydramine, promethazine, meclizine, cyclizine, and cinnarizine. [2] In pregnancy meclizine, dimenhydrinate and doxylamine are generally felt to be safe. [2] Side effects include sleepiness. [2] [41] Second generation antihistamines have not been found to be useful. [2]
The effects of theophylline/ephedrine as a performance-enhancing drug in exercise and sports have been studied. [20] [21] Use of theophylline/ephedrine combinations has led to disqualification of elite athletes due to ephedrine being banned in competitive sports. [22]
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Phenylephrine, sold under the brand names Neosynephrine and Sudafed PE among others, is a medication used as a decongestant for uncomplicated nasal congestion in the form of a nasal spray or oral tablet, [5] to dilate the pupil, to increase blood pressure given intravenously in cases of low blood pressure, and to relieve hemorrhoids as a suppository.
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109 S High St #100, Columbus, OH · Directions · (614) 224-4261
"GoodRx app has saved consumers $10 billion." - Fox Business