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  2. Dapagliflozin - Wikipedia

    en.wikipedia.org/wiki/Dapagliflozin

    The combination drug was approved for medical use in the United States in February 2017, where it also is sold under the brand name Qtern. [ 61 ] [ 62 ] In May 2019, the fixed-dose combination of dapagliflozin, saxagliptin, and metformin hydrochloride as extended-release tablets was approved in the United States to improve glycemic control in ...

  3. What Does This New Diabetes Drug Mean for AstraZeneca ... - AOL

    www.aol.com/news/2014-01-15-new-diabetes-drug...

    Recently, two pharmaceutical giants received FDA approval for a new treatment for type 2 diabetes. Farxiga (dapagliflozin) is a "sodium-glucose co-transporter 2 inhibitor", or SGLT2 inhibitor for ...

  4. 19 drug approvals in 2024 that had 'big clinical impact ... - AOL

    www.aol.com/news/19-drug-approvals-2024-had...

    GoodRx released a list of 19 of the most influential drugs and vaccines approved by the FDA in 2024 to treat a variety of conditions. These medications are “slated to make a big clinical impact."

  5. SGLT2 inhibitor - Wikipedia

    en.wikipedia.org/wiki/SGLT2_inhibitor

    Sotagliflozin (Inpefa) is a dual SGLT1/SGLT2 inhibitor approved by the US Food and Drug Administration (FDA) in May 2023, to reduce the risk of cardiovascular death, hospitalization for heart failure, and urgent heart failure visit in adults with heart failure or type 2 diabetes, chronic kidney disease, and other cardiovascular risk factors.

  6. Dapagliflozin/metformin - Wikipedia

    en.wikipedia.org/wiki/Dapagliflozin/metformin

    To lessen the risk of developing ketoacidosis (a serious condition in which the body produces high levels of blood acids called ketones) after surgery, the FDA has approved changes to the prescribing information for SGLT2 inhibitor diabetes medicines to recommend they be stopped temporarily before scheduled surgery. Canagliflozin, dapagliflozin ...

  7. AstraZeneca plc (ADR) Hopes Farxiga Can Go Far - AOL

    www.aol.com/news/2014-01-09-astrazeneca-plc-adr...

    AstraZeneca's SGLT-2 inhibitor dapaglifozin has had a difficult path to market, but the company finally got the FDA's go-ahead to market the drug on Wednesday. While SGLT-2 inhibitors are a promising

  8. PDUFA date - Wikipedia

    en.wikipedia.org/wiki/PDUFA_date

    The PDUFA date serves as a good first approximation of when a final decision on drug approval can be expected. Sponsors frequently publish PDUFA dates for their pending applications, [1] and while there is no official list of PDUFA dates, [10] several websites collect PDUFA dates from press announcements in a calendar form.

  9. AstraZeneca's Farxiga Flunks Late-Stage COVID-19 Study - AOL

    www.aol.com/news/astrazenecas-farxiga-flunks...

    AstraZeneca plc (NASDAQ: AZN) presented detailed data from the DARE-19 Phase 3 trial at the American College of Cardiology, evaluating Farxiga (dapagliflozin) to treat hospitalized COVID-19 ...