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Atrial fibrillation (AF, AFib or A-fib) is an abnormal heart rhythm (arrhythmia) characterized by rapid and irregular beating of the atrial chambers of the heart. [ 11 ] [ 12 ] It often begins as short periods of abnormal beating , which become longer or continuous over time. [ 4 ]
Defects in cellular processes such as autophagy and mitophagy are thought to contribute to the development of diabetic cardiomyopathy. [2] Diabetic cardiomyopathy is characterized functionally by ventricular dilation, enlargement of heart cells, prominent interstitial fibrosis and decreased or preserved systolic function [5] in the presence of a diastolic dysfunction.
A heart attack requires immediate treatment to improve blood flow to your heart, relieve your symptoms, and prevent another heart attack. Some treatment options include: Some treatment options ...
Hypertension or high blood pressure affects at least 26.4% of the world's population. [15] Hypertensive heart disease is only one of several diseases attributable to high blood pressure. Other diseases caused by high blood pressure include ischemic heart disease, cancer, stroke, peripheral arterial disease, aneurysms and kidney disease.
It is, however, a major risk factor for stroke, coronary artery disease, heart failure, atrial fibrillation, peripheral arterial disease, vision loss, chronic kidney disease, and dementia. [2] [3] [4] [12] Hypertension is a major cause of premature death worldwide. [13]
Excessive blood sugar levels have the potential to harm tissues and cells. [4] A form of cerebrovascular illness known as Cerebral Amyloid Angiopathy (CAA) is typified by the buildup of amyloid beta-peptide in the leptomeninges and small to medium sized cerebral blood vessels. [5] Amyloid buildup causes brittle blood vessels, which can lead to ...
The incidence of stroke rises progressively with increasing blood pressure levels, particularly systolic blood pressure in individuals >65 years. Treatment of hypertension convincingly decreases the incidence of both ischemic and hemorrhagic strokes. [41] Hypertension is also associated with impaired cognition in an aging population.
NPPA variants affect plasma ANP concentrations, blood pressure levels, and cardiovascular diseases such as atrial fibrillation (AF). [11] ANP-deficient mice were found to have a large increase in heart and left ventricular weight in response to volume overload, which is normally prevented by proper regulation of blood pressure. [12]
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