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Neonatal sepsis is a type of neonatal infection and specifically refers to the presence in a newborn baby of a bacterial blood stream infection (BSI) (such as meningitis, pneumonia, pyelonephritis, or gastroenteritis) in the setting of fever. Older textbooks may refer to neonatal sepsis as "sepsis neonatorum".
Neonatal sepsis of the newborn is an infection that has spread through the entire body. The inflammatory response to this systematic infection can be as serious as the infection itself. [ 26 ] In infants that weigh under 1500 g, sepsis is the most common cause of death.
It's also a well-known pathogen in neonatal sepsis, where genetic fingerprinting has shown its ability for clonal nosocomial dissemination; [3] S. capitis may cause late-onset sepsis in pre-term neonates, possibly by first colonising the immature - and consequently more permeable - neonatal gut before entering the bloodstream from the gut. [9]
Omphalitis of newborn is the medical term for inflammation of the umbilical cord stump in the neonatal newborn period, most commonly attributed to a bacterial infection. [1] Typically immediately after an infant is born, the umbilical cord is cut with a small remnant (often referred to as the stump) left behind.
Pneumopericardium is a medical condition where air enters the pericardial cavity.This condition has been recognized in preterm neonates, in which it is associated with severe lung pathology, after vigorous resuscitation, or in the presence of assisted ventilation. [2]
Early onset neonatal sepsis [21] Septic shock; Neonatal pneumonia; Infant respiratory distress; In the long-term, infants may be more likely to experience cerebral palsy or neurodevelopmental disabilities. Disability development is related to the activation of the fetal inflammatory response syndrome (FIRS) when the fetus is exposed to infected ...
At Month 4, particularly deep responses were observed in participants without prior exposure to biologic therapies (n=7), including complement or neonatal fragment crystallizable receptor (FcRn) inhibitors, with an average MG-ADL reduction of 6.6 (±1.5).
In the western world, GBS (in the absence of effective prevention measures) is the major cause of several bacterial infections of the newborn neonatal infection sepsis, pneumonia, and meningitis, which can lead to death or long-term sequelae. [3] GBS neonatal infection typically originates in the lower reproductive tract of infected mothers.