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The outbreak of yellow fever in Barcelona in 1821. The evolutionary origins of yellow fever are most likely African. [1] [2] Phylogenetic analyses indicate that the virus originated from East or Central Africa, with transmission between primates and humans, and spread from there to West Africa. [3]
The first human virus to be identified was the yellow fever virus. [6] In 1881, Carlos Finlay (1833–1915), a Cuban physician, first conducted and published research that indicated that mosquitoes were carrying the cause of yellow fever, [7] a theory proved in 1900 by commission headed by Walter Reed (1851–1902).
The Flaviviridae are part of RNA virus supergroup II, which includes certain plant viruses and bacterial viruses. [2] The family has four genera: [1] [2] Genus Flavivirus, renamed Orthoflavivirus in 2023, (includes Dengue virus, Japanese encephalitis, Kyasanur Forest disease, Powassan virus, West Nile virus, Yellow fever virus, and Zika virus)
Yellow fever virus. This disease is transmitted by the bite of female mosquito; the higher prevalence of transmission by Aedes aegypti has led to it being known as the Yellow Fever Mosquito. The transmission of yellow fever is entirely a matter of available habitat for vector mosquito and prevention such as mosquito netting. They mostly infect ...
Flavivirus, renamed Orthoflavivirus in 2023, [3] is a genus of positive-strand RNA viruses in the family Flaviviridae.The genus includes the West Nile virus, dengue virus, tick-borne encephalitis virus, yellow fever virus, Zika virus and several other viruses which may cause encephalitis, [4] as well as insect-specific flaviviruses (ISFs) such as cell fusing agent virus (CFAV), Palm Creek ...
Finlay's work, carried out during the 1870s, finally came to prominence in 1900. He was the first to theorize, in 1881, that a mosquito was a carrier, now known as a disease vector, of the organism causing yellow fever: a mosquito that bites a victim of the disease could subsequently bite and thereby infect a healthy person. [4]
Aedes aegypti (UK: / ˈ iː d iː z /; US: / eɪ d z / or / ˈ eɪ d iː z / from Greek αηδής 'hateful' and / eɪ ˈ dʒ ɪ p t i / from Latin, meaning 'of Egypt'), the yellow fever mosquito, is a mosquito that can spread dengue fever, chikungunya, Zika fever, Mayaro and yellow fever viruses, and other disease agents.
Flaviviridae viruses transmissible via vectors like mosquitoes include West Nile virus and yellow fever virus, which are single stranded, positive-sense RNA viruses enveloped in a protein coat. Once inside the host's body, the virus will attach itself to a cell's surface through receptor-mediated endocytosis.