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The exact mechanism of the condition is unknown. Some studies have suggested the itching occurs in response to increased fibrinolytic activity in the skin, [5] [6] inappropriate activation of the sympathetic nervous system, [7] increased activity of acetylcholinesterase, [8] [9] or an increase in mast cell degranulation that releases histamine and other chemicals into the body.
Dermatophytosis, also known as tinea and ringworm, is a fungal infection of the skin [2] (a dermatomycosis), that may affect skin, hair, and nails. [1] Typically it results in a red, itchy, scaly, circular rash. [1] Hair loss may occur in the area affected. [1] Symptoms begin four to fourteen days after exposure. [1]
Lichen simplex chronicus (LSC) is thick leathery skin with exaggerated skin markings caused by sudden itching and excessive rubbing and scratching. [1] It generally results in small bumps, patches, scratch marks and scale. [1] It typically affects the neck, scalp, upper eyelids, ears, palms, soles, ankles, wrists, genital areas and bottom. [1]
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The foundation stone was laid by Joseph Butler, the Bishop of Durham, on 5 September 1751, following the proposals of Richard Lambert. [1] It opened on 8 October 1753. [ 2 ] By the end of the 19th century, despite major extensions including the Dobson Wing which opened in 1855 [ 3 ] and the Ravensworth Wards which opened in 1885, [ 4 ] the ...
The back, legs, arms, scalp, and genitalia are areas of the body that are commonly affected by senile pruritus. [3] According to a study, most of the people who experience pruritus daily have increased itching sensations and other associated symptoms during the night. Most studies reveal that senile pruritus is more common in men than women. [3]
Typically, over the upper inner thighs, there is an intensely itchy red raised rash with a scaly well-defined curved border. [3] [4] It is often associated with athlete's foot and fungal nail infections, excessive sweating, and sharing of infected towels or sports clothing. [4] [5] [6] It is uncommon in children. [4]
The condition remains localized to the skin. [3] [6] Skin temperature: The affected areas may feel warm to the touch due to the inflammatory process. [3] Pigmentation changes: In some cases, particularly in individuals with darker skin tones or after repeated episodes, the affected areas may show temporary hyperpigmentation (darkening of the skin).