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Acral nevi may occur in all ethnic groups, but are more common in dark-skinned people. The acral nevus is a benign skin lesion that can occur at any age, but is generally noticed between 10 and 30 years of age. Both children and adults may be observed with this skin lesion.
Nevi and melanomas are a group of neoplasia. Although a nevus and a melanoma are often treated as independent entities, there is evidence that a nevus can be a precursor for a melanoma. [1] Common mutations have been identified in nevi and melanomas. [2] [3] [4]
Dermatoscopy, also known as dermoscopy [1] or epiluminescence microscopy, is the examination of skin lesions with a dermatoscope. It is a tool similar to a camera to allow for inspection of skin lesions unobstructed by skin surface reflections.
Melanocytic tumors of uncertain malignant potential (MELTUMP) are melanocytic lesions in the dermis that cannot be classified by morphology as either benign naevi (moles) or malignant melanomas because the mass shows features of both.
Nevi are typically diagnosed clinically with the naked eye or using dermatoscopy. More advanced imaging tests are available for distinguishing melanocytic nevi from melanoma, including computerized dermoscopy and image analysis. [14] The management of nevi depends on the type of nevus and the degree of diagnostic uncertainty.
However, a melanocytic nevus is benign, and melanoma is malignant. Most melanocytic nevi never evolve into a cancer, with the lifetime risk for an individual nevus being 1 in 3000 for men and 1 in 11 000 for women. [5] Moreover, dermatologists have a standardized system for determining whether a skin lesion is suspicious for malignant melanoma.
Melanocytic nevi and neoplasms are caused by either a proliferation of (1) melanocytes, or (2) nevus cells, a form of melanocyte, but which lack dendritic processes. Contents Top
Melanocytic nevi and neoplasms are caused by either a proliferation of (1) melanocytes, or (2) nevus cells, a form of melanocyte that lack dendritic processes. [78] [79] Acral nevus (melanocytic nevus of acral skin, melanocytic nevus with intraepidermal ascent of cells) Amelanotic blue nevus (hypomelanotic blue nevus) Becker's nevus; Balloon ...