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N,N-Dimethyltryptamine (DMT or N,N-DMT) is a substituted tryptamine that occurs in many plants and animals, including humans, and which is both a derivative and a structural analog of tryptamine. [1] [2] [3] DMT is used as a psychedelic drug and prepared by various cultures for ritual purposes as an entheogen. [9]
6-MeO-DMT, or 6-methoxy-N,N-dimethyltryptamine, also known as 6-OMe-DMT, is a serotonergic drug of the tryptamine family. [ 1 ] [ 2 ] It is the 6- methoxy derivative of the serotonergic psychedelic N , N -dimethyltryptamine (DMT) and is a positional isomer of the serotonergic psychedelic 5-MeO-DMT .
Later analysis tentatively found 5-MeO-DMT in stems, leaves and roots; DMT, NMT and 5-MeO-DMT were tentatively observed in seeds, but follow-up tests were negative. [ 9 ] [ 53 ] Bark contains unidentified alkaloids [ 54 ] Bark in one sample subsequently found to contain an alkaloid which has an Rf value suggesting DMT.
As with DMT, CYB004 is a potent agonist of the serotonin 5-HT 2A receptor and produces psychedelic-like effects in animals. [ 1 ] [ 5 ] [ 3 ] However, CYB004, due to its deuteration, is more resistant to metabolism than DMT and shows a longer elimination half-life (by 2.5- to 2.9-fold) and slower clearance (by 38 to 55%) in animals. [ 3 ]
2,α-Dimethyltryptamine (2,α-DMT) is a tryptamine and a lesser-known psychedelic drug. It is the 2,α-dimethyl analog of DMT. Its synthesis was first reported in 1965. [1] Alexander Shulgin lists the dosage as 300-500 mg, and the duration as 7–10 hours in his book TiHKAL (Tryptamines I Have Known and Loved). [2] 2,α-DMT causes mydriasis and ...
Psilocin, also known as 4-hydroxy-N,N-dimethyltryptamine (4-OH-DMT), is a substituted tryptamine alkaloid and a serotonergic psychedelic. It is present in most psychedelic mushrooms [ 7 ] together with its phosphorylated counterpart psilocybin .
In thermodynamic terms, all organic tissues are composed of chemical energy, which, when not maintained by the constant biochemical maintenance of the living organism, begin to chemically break down due to the reaction with water into amino acids, known as hydrolysis. The breakdown of the proteins of a decomposing body is a spontaneous process.
Bufotoxins can contain 5-MeO-DMT, bufagins, bufalin, bufotalin, bufotenin, bufothionine, dehydrobufotenine, epinephrine, norepinephrine, and serotonin. Some authors have also used the term bufotoxin to describe the conjugate of a bufagin with suberylarginine. [4] The toxic substances found in toads can be divided by chemical structure in two ...