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The long-term goal is to improve outcome by reducing stroke-related disability and mortality. Options for reperfusion therapy that are proven effective include intravenous thrombolysis with alteplase or tenecteplase, and mechanical thrombectomy.
Two randomized trials, CADISS (Cervical Artery Dissection in Stroke Study) and TREAT-CAD (Biomarkers and Antithrombotic Treatment in Cervical Artery Dissection), have examined anticoagulation versus antiplatelet therapy for cervical artery dissection.
The European Stroke Organization (ESO) has recently released a specific guideline for the management of dissections. 1 Cervicocephalic dissections are arteriopathies defined by the presence of a hematoma in the arterial wall. 2 Dissection is less common than atherosclerosis in the general population, but a main mechanism of stroke in younger ...
This topic will review the pathophysiology, etiology, clinical features, and diagnosis of cerebral and cervical artery dissection. The treatment and prognosis of cervicocephalic dissection is reviewed in detail separately.
For cervical artery dissection (CeAD) we used the term extracranial artery dissection (EAD) for clear differentiation from intracranial artery dissection (IAD). EAD refers to the dissection of a cervical carotid or vertebral artery radiologically confirmed by the presence of a mural hematoma, a dissecting aneurysm, a
In cerebral artery dissection without intracranial hemorrhage, treatment was based on individual clinical presentation, degree of stenosis, recurrent symptoms, or image findings. Favorable functional outcomes were determined using modified Rankin Scale (mRS) scores of 0–2.
This review summarizes recent therapeutic advances in cervical (CeAD) and intracranial artery dissection (IAD) research. Despite unproven benefits, but in the absence of any signal of harm, in patients, with acute ischemic stroke attributable to CeAD, intravenous thrombolysis and, in case of large-vessel occlusion, endovascular ...
Cerebral artery dissection is encountered in many hospitals. At our hospital, we have treated 107 patients with cerebral arterial dissection (including strongly suspicious and clinically suspicious cases) between January 1997 and July 2015 (71 men and 36 women; mean age, 59.2 ± 14.8 years).
Intracranial artery dissection (IAD) can be associated with severe clinical consequences yet have favorable outcomes when treated properly. Mayo Clinic has experience managing this rare and challenging condition.
The treatment and outcomes of blunt cerebrovascular injury are reviewed here. Treatment strategies include antithrombotic therapy, endovascular intervention, and surgical repair.