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Common side effects of buspirone include nausea, headaches, dizziness, and difficulty concentrating. [10] [12] Serious side effects may include movement disorders, serotonin syndrome, and seizures. [12] Its use in pregnancy appears to be safe but has not been well studied, and use during breastfeeding has not been well studied either. [12] [13]
Cerebrovascular accident (stroke); Myocardial infarction (heart attack); Cardiomyopathy; Congestive heart failure; Bradycardia; Dysphoria; Hallucinations; Feelings of ...
A common metabolite of several azapirones including buspirone, gepirone, ipsapirone, revospirone, and tandospirone is 1-(2-pyrimidinyl)piperazine (1-PP). [47] [48] [49] 1-PP possesses 5-HT 1A partial agonist and α 2-adrenergic antagonist actions and likely contributes overall mostly to side effects. [47] [48] [50]
Buspirone is sometimes used off-label to reduce sexual dysfunction associated with the use of SSRIs. [54] [55] [56] A number of non-SSRI drugs are not associated with sexual side effects (such as bupropion, mirtazapine, tianeptine, agomelatine, tranylcypromine, and moclobemide [57] [58] [59]).
Gepirone is indicated for the treatment of major depressive disorder (MDD) in adults. [1] Of 15 clinical trials of gepirone for major depressive disorder submitted to the U.S. Food and Drug Administration (FDA), three were excluded for methodological reasons, three were deemed "failed" and "uninformative", seven were deemed negative and did not demonstrate effectiveness, and two were deemed ...
Side effects [27] Muscle weakness; Fatigue; Rhabdomyolysis; Hepatotoxicity; Used for risk factor control; If the maximum dose of statin cannot achieve the patient's goal, combination with ezetimibe is recommended. [17] An image of rosuvastatin tablets (Crestor) Caution
New RSV vaccines are now available to help prevent serious infection in people over 60. Doctors explain the RSV vaccine and its side effects in older adults.
Tandospirone is most commonly used as a treatment for anxiety and depressive disorders, such as generalised anxiety disorder and dysthymia respectively. [3] For both indications it usually takes a couple of weeks for therapeutic effects to begin to be seen, [3] although at higher doses more rapid anxiolytic responses have been seen. [4]