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A new rumor claims that Paxlovid, Pfizer's Covid drug, is merely a "dressed up" ivermectin molecule with little difference other than price. The term "Pfizermectin" is even being used to emphasize this. But biochemical and pharmacokinetic data say otherwise. Here are the numbers.
This helpful infographic compares newly approved antiviral Paxlovid to ivermectin in regard to treating COVID-19.
Compare Ivermectin vs Paxlovid head-to-head with other drugs for uses, ratings, cost, side effects and interactions.
Since in most countries ivermectin has not been approved for COVID treatment, performing ivermectin vs. placebo studies appears to be unethical when these two newer drugs have been officially approved by health-authorities.
Paxlovid combines two medicines. The first, called nirmatrelvir, blocks the activity of an enzyme the COVID-19 virus needs to copy itself, also called replicate. The second medicine, called ritonavir, helps slow the breakdown of nirmatrelvir.
Abstract. The COVID-19 pandemic has accelerated the study of drugs, most notably ivermectin and more recently Paxlovid (PF-07321332) which is in phase III clinical trials with experimental data showing covalent binding to the viral protease M pro.Theoretical developments of catalytic site-directed docking support thermodynamically feasible non-covalent binding to M pro.
To evaluate the efficacy of ivermectin for the prevention of progression of Covid-19 resulting in hospitalization among outpatients with SARS-CoV-2 infection, we conducted a randomized,...
Merck and Pfizer are each developing a new oral antiviral drug that might prevent or treat COVID-19. The pills are very different from the antiparasitic medication ivermectin, contrary to claims...
Applies to: Paxlovid (nirmatrelvir / ritonavir) and ivermectin. Ritonavir may increase the blood levels and effects of ivermectin. You may need a dose adjustment or more frequent monitoring by your doctor to safely use both medications. Contact your doctor if your condition changes or you experience increased side effects.
Paxlovid, an oral antiviral pill that can be taken at home, is the go-to treatment for COVID-19. If you are at high risk for severe disease from COVID, and you take it within the first five days of experiencing symptoms, it will lower your risk of getting so sick that you need to be hospitalized.