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Histidine ball and stick model spinning. Histidine (symbol His or H) [2] is an essential amino acid that is used in the biosynthesis of proteins.It contains an α-amino group (which is in the protonated –NH 3 + form under biological conditions), a carboxylic acid group (which is in the deprotonated –COO − form under biological conditions), and an imidazole side chain (which is partially ...
The triad of cytomegalovirus protease [b] uses histidine as both the acid and base triad members. Removing the acid histidine results in only a 10-fold activity loss (compared to >10,000-fold when aspartate is removed from chymotrypsin). This triad has been interpreted as a possible way of generating a less active enzyme to control cleavage ...
Download as PDF; Printable version; In other projects ... Chemical formula: C 6 H 9 N 3 O 2 ... (L-histidine) ^a CID 71083 from ...
The midpoint of the titration curve corresponds to the pK a, or the pH where the ratio of protonated: deprotonated molecules is 1:1. Continuing with the T4 lysozyme example, a titration curve is obtained through observation of a shift in the C2 proton of histidine 31 (Figure 5).
The 21 proteinogenic α-amino acids found in eukaryotes, grouped according to their side chains' pK a values and charges carried at physiological pH (7.4) 2- , alpha- , or α-amino acids [ 21 ] have the generic formula H 2 NCHRCOOH in most cases, [ b ] where R is an organic substituent known as a " side chain ".
Chemical Agents Warning Properties Latency Period Initial Symptoms Blister Agents Lewisite Gas: colorless Odor: geraniums Seconds to minutes
The isoelectric point (pI, pH(I), IEP), is the pH at which a molecule carries no net electrical charge or is electrically neutral in the statistical mean. The standard nomenclature to represent the isoelectric point is pH(I). [ 1 ]
Background Chlorine and caustic soda are produced at chlor-alkali plants using mercury cells or the increasingly popular membrane technology that is mercury free and more energy-