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Asplenia with cardiovascular anomalies, also known as Ivemark syndrome and right atrial isomerism, [1] is an example of a heterotaxy syndrome.These uncommon congenital disorders are characterized by defects in the heart, spleen and paired organs such as the lungs and kidneys.
Splenic artery aneurysms are rare, but still the third most common abdominal aneurysm, after aneurysms of the abdominal aorta and iliac arteries. [2] [3] They may occur in pregnant women in the third trimester and rupture carries a maternal mortality of greater than 50% and a fetal mortality of 70 to 90%.
Enlargement of the spleen is a requirement for the diagnosis of SMZL and is seen in nearly all people affected by SMZL (often without lymphadenopathy). [1] Aside from the uniform involvement of the spleen, the bone marrow is frequently positive in patients with SMZL displaying a nodular pattern with morphology similar to what is observed in the splenic hilar lymph nodes. [7]
Splenic infarction is a condition in which blood flow supply to the spleen is compromised, [1] leading to partial or complete infarction (tissue death due to oxygen shortage) in the organ. [2] Splenic infarction occurs when the splenic artery or one of its branches are occluded, for example by a blood clot .
Watershed area is the medical term referring to regions of the body, [1] that receive dual blood supply from the most distal branches of two large arteries, such as the splenic flexure of the large intestine. The term refers metaphorically to a geological watershed, or drainage divide, which separates adjacent drainage basins. For example, the ...
The celiac lymph nodes are grouped into three sets: the gastric, hepatic and splenic lymph nodes. [citation needed] They receive lymph from the stomach, duodenum, pancreas, spleen, liver, and gall bladder. [1]
Acquired asplenia occurs for several reasons: . Following splenectomy due to splenic rupture from trauma or because of tumor; After splenectomy with the goal of interfering with splenic function, as a treatment for diseases (e.g. idiopathic thrombocytopenic purpura, thalassemia, spherocytosis), in which the spleen's usual activity exacerbates the disease
Splenic artery embolization is a minimally invasive procedure and, where successful, avoids splenectomy. If an individual's spleen is enlarged, as is frequent in mononucleosis, most physicians will advise against activities (such as contact sports) where injury to the abdomen could be catastrophic. [10]