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  2. Morningness–eveningness questionnaire - Wikipedia

    en.wikipedia.org/wiki/Morningness–eveningness...

    A study in 2009 examined differences between evening and morning types in the timing of melatonin and core body temperature rhythms as well as objective and subjective sleepiness rhythms in a controlled laboratory protocol. The evening types had significantly later timed rhythms for all these variables, particularly that of maximum alertness ...

  3. Phase response curve - Wikipedia

    en.wikipedia.org/wiki/Phase_response_curve

    Phase response curves for light and for melatonin administration. In humans and animals, there is a regulatory system that governs the phase relationship of an organism's internal circadian clock to a regular periodicity in the external environment (usually governed by the solar day).

  4. Melatonin - Wikipedia

    en.wikipedia.org/wiki/Melatonin

    Melatonin, an indoleamine, is a natural compound produced by various organisms, including bacteria and eukaryotes. [1] Its discovery in 1958 by Aaron B. Lerner and colleagues stemmed from the isolation of a substance from the pineal gland of cows that could induce skin lightening in common frogs.

  5. Circadian rhythm - Wikipedia

    en.wikipedia.org/wiki/Circadian_rhythm

    A circadian rhythm (/ s ər ˈ k eɪ d i ə n /), or circadian cycle, is a natural oscillation that repeats roughly every 24 hours.Circadian rhythms can refer to any process that originates within an organism (i.e., endogenous) and responds to the environment (is entrained by the environment).

  6. Which is better for sleep: Magnesium or melatonin? - AOL

    www.aol.com/lifestyle/better-sleep-magnesium...

    “I recommend melatonin to patients who might have circadian rhythm disorders or if they are older,” he says. As far as effectiveness, Zweig doesn’t believe there’s a uniform answer.

  7. Melatonin as a medication and supplement - Wikipedia

    en.wikipedia.org/wiki/Melatonin_as_a_medication...

    Melatonin is thought to activate melatonin receptors in the suprachiasmatic nucleus of the hypothalamus to regulate the circadian clock and sleep–wake cycles. [21] When used several hours before sleep according to the phase response curve for melatonin in humans, small amounts (0.3 mg [ 56 ] ) of melatonin shift the circadian clock earlier ...

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