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Voltage-gated chloride channels perform numerous crucial physiological and cellular functions, such as controlling pH, volume homeostasis, transporting organic solutes, regulating cell migration, proliferation, and differentiation. Based on sequence homology the chloride channels can be subdivided into a number of groups.
chlorine: 17: 5a: Chlorine salts are critical for many species, including humans. [11] Its ion is used as an electrolyte, as well as making the hydrochloric acid the stomach uses for digestion. [36] Excessive blood chlorides (hyperchloemia) are a symptom of several diseases; but the condition itself does not have symptoms. [37] Elemental Cl 2 ...
An ionocyte (formerly called a chloride cell) is a mitochondrion-rich cell within ionoregulatory organs of animals, such as teleost fish gill, insect Malpighian tubules, crustacean gills, antennal glands and maxillary glands, and copepod Crusalis organs. [1]
Aluminium, the third most common element in the Earth's crust (after oxygen and silicon), serves no function in living cells, but is toxic in large amounts, depending on its physical and chemical forms and magnitude, duration, frequency of exposure, and how it was absorbed by the human body. [38] Transferrins can bind aluminium. [39]
The term chloride refers to a compound or molecule that contains either a chlorine anion (Cl −), which is a negatively charged chlorine atom, or a non-charged chlorine atom covalently bonded to the rest of the molecule by a single bond (−Cl). The pronunciation of the word "chloride" is / ˈ k l ɔːr aɪ d /. [3]
Chloride is an anion in the human body needed for metabolism (the process of turning food into energy). [1] It also helps keep the body's acid-base balance. The amount of serum chloride is carefully controlled by the kidneys. [2] Chloride ions have important physiological roles.
While the specific function of this protein is not well understood, it belongs to a family of proteins, called anoctamins, that act as chloride channels. Chloride channels, which transport negatively charged chlorine atoms (chloride ions) in and out of cells, play a key role in a cell's ability to generate and transmit electrical signals.
Chlorine, along with phosphorus, is the sixth most common element in organic matter. [1] Cells utilize chloride to balance pH and maintain turgor pressure at equilibrium. The high electrical conductivity of Cl − ions are essential for neuron signalling in the brain and regulate many other essential functions in biology [9]