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Dupuytren's contracture of the right little finger. Arrow marks the area of scarring. Typically, Dupuytren's contracture first presents as a thickening or nodule in the palm, which initially can be with or without pain. [12] Later in the disease process, which can be years later, [13] there is increasing loss of range of motion of the affected ...
Dupuytren's contracture Guillaume Dupuytren, Baron Dupuytren ( UK : / ˌ dj uː p w iː ˈ t r æ̃ , dj uː ˈ p w iː t r ɛ n / , [ 1 ] US : / d ə p w iː ˈ t r æ̃ , d ə ˈ p w iː t r ən / , [ 2 ] French: [ɡijom dypɥitʁɛ̃] ; 5 October 1777 – 8 February 1835) was a French anatomist and military surgeon .
Many of these deformities, such as Dupuytren's contracture, swan-neck deformity etc. can be associated with both a chronic, progressive event, or an acute injury; [17] such as boutonnière deformity, which can be caused by trauma, [1] or induced by a chronic condition like rheumatoid arthritis. [20]
In adjunct with surgery, refractory muscle contracture can also be treated with Botulinum toxins A and B; however, the effectiveness of the toxin is slowly lost over time, and most patients need a single treatment to correct muscle contracture over the first few weeks after surgery. [21] Shortening of the surgically lengthened muscle can re-occur.
As of the 2010s, there is a "clear consensus" [2] from medical groups, including the European Organization for Research and Treatment of Cancer Soft Tissue and Bone Sarcoma Group and the European Society for Medical Oncology: immediate surgical resection is no longer the first-line treatment, particularly in asymptomatic patients.
Treatment is mainly surgical; radiotherapy or chemotherapy is usually an indication of relapse. [clarification needed] Head and neck desmoid fibromatosis is a serious condition due to local aggression, specific anatomical patterns and the high rate of relapse. For children surgery is particularly difficult, given the potential for growth disorders.
In pathology, a contracture is a shortening of muscles, tendons, skin, and nearby soft tissues that causes the joints to shorten and become very stiff, preventing normal movement. [ 1 ] [ 2 ] A contracture is usually permanent, but less commonly can be temporary (such as in McArdle disease ), [ 3 ] or resolve over time but reoccur later in life ...
Knuckle pads are benign subcutaneous fibrotic nodules that are seen in the finger joints and/or the extensor area of the foot. [6] [7] [8] From a clinical perspective, these are well-defined, non-compressible, freely moveable lesions that resemble warts and primarily affect the dorsal portion of the proximal interphalangeal (PIP) and, less frequently, the metacarpophalangeal (MCP) joints.
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