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Different layers of kidney depicted in a 3D medical Illustration. The renal capsule is a tough fibrous layer surrounding the kidney and covered in a layer of perirenal fat known as the adipose capsule of kidney. The adipose capsule is sometimes included in the structure of the renal capsule. It provides some protection from trauma and damage.
Each kidney, with its adrenal gland is surrounded by two layers of fat: the perirenal fat present between renal fascia and renal capsule and pararenal fat superior to the renal fascia. The human kidney is a bean-shaped structure with a convex and a concave border. [14]
The renal fascia is a dense, elastic connective tissue envelope enclosing the kidney and adrenal gland, together with the layer of perirenal fat surrounding these two. [1]The renal fascia separates the adipose capsule of kidney from the overlying pararenal fat.
The glomerulus and its surrounding Bowman's capsule constitute a renal corpuscle, the basic filtration unit of the kidney. [2] The rate at which blood is filtered through all of the glomeruli, and thus the measure of the overall kidney function, is the glomerular filtration rate.
The Bowman's capsule has an outer parietal layer composed of simple squamous epithelium. The visceral layer, composed of modified simple squamous epithelium, is lined by podocytes, podocyte foot processes (pedicels), that wrap around glomerular capillaries. These pedicels interdigitate with pedicels of adjacent podocytes forming filtration slits.
A healthy adult has 1 to 1.5 million nephrons in each kidney. [1]: 22 Blood is filtered as it passes through three layers: the endothelial cells of the capillary wall, its basement membrane, and between the podocyte foot processes of the lining of the capsule.
The outer layer of each kidney is made up of a fibrous sheath called a renal capsule. The peripheral layer of the kidney is called the cortex, and the inner layer is called the medulla. The medulla consists of pyramids (also called malpighian pyramids), ascending with their base to the cortex and forming together with it the renal lobe. [59]
Podocytes are cells in Bowman's capsule in the kidneys that wrap around capillaries of the glomerulus.Podocytes make up the epithelial lining of Bowman's capsule, the third layer through which filtration of blood takes place. [1]