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CCR5-Δ32 (or CCR5-D32 or CCR5 delta 32) is an allele of CCR5. [42] [43] CCR5 Δ32 is a 32-base-pair deletion that introduces a premature stop codon into the CCR5 receptor locus, resulting in a nonfunctional receptor. [44] [45] CCR5 is required for M-tropic HIV-1 virus entry. [46]
It has mutations in the gene encoding the SARS-CoV-2 spike protein [6] causing the substitutions T478K, P681R and L452R, [7] [8] which are known to affect transmissibility of the virus as well as whether it can be neutralised by antibodies for previously circulating variants of the COVID-19 virus. [9]
The continued spread of the SARS-CoV-2 virus has spawned a Greek alphabet of variants - a naming system used by the World Health Organization to track concerning new mutations of the virus that ...
SARS-CoV-2 is the virus that causes coronavirus disease 2019 (COVID-19). Some have been stated, to be of particular importance due to their potential for increased transmissibility, [1] increased virulence, or reduced effectiveness of vaccines against them. [2] [3] These variants contribute to the continuation of the COVID-19 pandemic.
The Delta variant is the fastest, fittest and most formidable version of the coronavirus that causes COVID-19 the world has encountered, and it is upending assumptions about the disease even as ...
Here's what experts are saying about those findings and how they might affect the COVID-19 pandemic and efforts to develop vaccines and treatments.
Deltacoronavirus (Delta-CoV) is one of the four genera (Alpha-, Beta-, Gamma-, and Delta-) of coronaviruses. It is in the subfamily Orthocoronavirinae of the family Coronaviridae. They are enveloped, positive-sense, single-stranded RNA viruses. Deltacoronaviruses infect mostly birds and some mammals.
India said on Wednesday it has found around 40 cases of the Delta coronavirus variant carrying a mutation that appears to make it more transmissible, and advised states to increase testing.