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The underlying cause is due to the defective migration of GNRH neurons from olfactory placode to hypothalamus, leading to congenital GNRH deficiency. This leads to olfactory problems such as anosmia, optic defects like color blindness, and results in hypothalmic deficiencies associated with low levels of LH, affecting sex hormone testosterone in males or estrogen and progesterone in females.
Currently, there is no definitive treatment for congenital anosmia, as the condition involves the absence or underdevelopment of the olfactory bulbs and tracts, which are critical for the sense of smell. Management primarily focuses on safety precautions and coping strategies to mitigate the risks associated with the inability to smell. [2] [4] [5]
The sense of smell should be tested individually in each nostril. [18] Many cases of congenital anosmia remain unreported and undiagnosed. Since the disorder is present from birth the individual may have little or no understanding of the sense of smell, hence is unaware of the deficit. [56] It may also lead to reduction of appetite. [57]
People can be born with no sense of smell, a condition called anosmia, ... “And when there is a pleasant smell, the brain tells the nose to increase the amount of air inhaled. It’s not ...
Anosmia is the inability to perceive odor, or in other words a lack of functioning olfaction.Many patients may experience unilateral or bilateral anosmia. A temporary loss of smell can be caused by a blocked nose or infection. In contrast, a permanent loss of smell may be caused by death of olfactory receptor neurons in the nose or by brain injury in which there is damage to the
Whiffing nasty things is a part of life—but a foul nose shouldn’t be. ENT doctors explain the reasons for a bad smell in your nose and how to get rid of it.
According to the CDC, symptoms may include: Fever or chills. Cough. Shortness of breath or difficulty breathing. Sore throat. Congestion or runny nose. New loss of taste or smell. Fatigue. Muscle ...
Hyposmia, or microsmia, [1] is a reduced ability to smell and to detect odors.A related condition is anosmia, in which no odors can be detected.Some of the causes of olfaction problems are allergies, nasal polyps, viral infections and head trauma.