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Alcohol was determined to increase the risk of developing breast cancer, liver cancer, colorectal cancer, esophageal cancers, pharyngeal cancer, laryngeal cancer, and oral cancer. In 2009, the group determined that acetaldehyde which is a metabolite of ethanol is also carcinogenic to humans.
To help lower alcohol-related cancer risk, the Surgeon General recommends that cancer warnings be placed on the labels of alcoholic beverages, including beer and wine. ... Acetaldehyde is a ...
Acetaldehyde and the oxidative stress from drinking also prompt DNA damage and cellular proliferation, which can lead to cancer. Alcohol can also mess with the gut microbiome, increasing ...
According to the advisory, alcohol consumption can cause cancer through four primary mechanisms.. First, alcohol breaks down into acetaldehyde in the body. Acetaldehyde is ametabolite (or the end ...
Metabolism of ethanol forms acetaldehyde before acetaldehyde dehydrogenase forms acetic acid, but with the enzyme inhibited, acetaldehyde accumulates. If one consumes ethanol while taking disulfiram, the hangover effect of ethanol is felt more rapidly and intensely ( disulfiram-alcohol reaction ).
The idea that acetaldehyde is the cause of the flush is also shown by the clinical use of disulfiram (Antabuse), which blocks the removal of acetaldehyde from the body via ALDH inhibition. The high acetaldehyde concentrations described share similarity to symptoms of the flush (flushing of the skin, accelerated heart rate, shortness of breath ...
"A study published in Lancet Oncology found that in 2020, at least 4% of the world's newly diagnosed cancer cases were caused by drinking alcohol, which has over 700,000 people just in that one ...
In 2020, there were over 450,000 new cancer cases associated with alcohol consumption, according to the CDC. ... Acetaldehyde attacks DNA cells, which regulate cell growth, and cells can grow out ...