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The first successful antiviral, aciclovir, is a nucleoside analogue, and is effective against herpesvirus infections. The first antiviral drug to be approved for treating HIV, zidovudine (AZT), is also a nucleoside analogue. An improved knowledge of the action of reverse transcriptase has led to better nucleoside analogues to treat HIV infections.
List of Antiviral Drugs Antiviral Use Manufacturer Component Type Year approved Abacavir: HIV: ViiV Healthcare: Nucleoside analogue reverse transcriptase inhibitor (NRTI) 1998 Acyclovir (Aciclovir) Herpes Simplex, chickenpox, [2] varicella zoster virus: GSK: guanosine analogue RTI 1981 Adefovir: Hepatitis B [3] Gilead Sciences RTI 2002 , 2003 ...
Ribavirin, also known as tribavirin, is an antiviral medication used to treat illness caused by respiratory syncytial virus (RSV) and hepatitis C virus (HCV) infections, as well as some viral hemorrhagic fevers. [1]
On Thursday, Roche Holdings AG (OTC:RHHBY) released positive topline results of the phase 3 CENTERSTONE study of Xofluza (baloxavir marboxil), an antiviral that showed a reduction in the ...
Aciclovir risks causing resistance to antiviral agents, and in 1% to 10% of cases can cause unpleasant side effects. [19] Aciclovir taken by mouth does not appear to decrease the risk of pain after shingles. [20] In those with herpes of the eye, aciclovir may be more effective and safer than idoxuridine. [21]
The antiviral can also lead to resistance to HIV medication, and if you have untreated HIV, it can affect HIV medication effectiveness in the future. If you plan on taking Lagevrio, adverse ...
Molnupiravir is a prodrug of the synthetic nucleoside derivative N 4-hydroxycytidine and exerts its antiviral action by introducing copying errors during viral RNA replication. [ 13 ] [ 14 ] Molnupiravir was originally developed to treat influenza at Emory University by the university's drug innovation company, Drug Innovation Ventures at Emory ...
BSAs could be divided into experimental and investigational agents, and approved drugs. BSAs work by inhibiting viral proteins (such as polymerases and proteases ) or by targeting host cell factors and processes exploited by different viruses during infection. [ 1 ]