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Large, high quality research has found small differences in the brain between ADHD and non-ADHD patients. [1] [15] Jonathan Leo and David Cohen, critics who reject the characterization of ADHD as a disorder, contended in 2003 and 2004 that the controls for stimulant medication usage were inadequate in some lobar volumetric studies, which makes it impossible to determine whether ADHD itself or ...
A genetic variant associated with ADHD has been found at higher frequency in more nomadic populations and those with more of a history of migration. [10] Consistent with this, the health status of nomadic Ariaal men was higher if they had the ADHD associated genetic variant (7R alleles), whereas in recently sedentary (non-nomadic) Ariaal ...
However, in rare cases, ADHD can be caused by a single event including traumatic brain injury, [42] [47] [48] [49] exposure to biohazards during pregnancy, [8] or a major genetic mutation. [50] As it is a neurodevelopmental disorder, there is no biologically distinct adult-onset ADHD except for when ADHD occurs after traumatic brain injury.
There is no single, unified theory that explains the cause of ADHD. Genetic factors are presumed important, and it has been suggested that environmental factors may affect how symptoms manifest. [20] [35] It is becoming increasingly accepted that individuals with ADHD have difficulty with "executive functioning". In higher organisms, such as ...
NF-1 is a complex multi-system human disorder caused by the mutation of a gene on chromosome 17 that is responsible for production of a protein, called neurofibromin 1, which is needed for normal function in many human cell types. NF-1 causes tumors along the nervous system which can grow anywhere on the body. NF-1 is one of the most common ...
Neurodevelopmental disorders are a group of neurological differences affecting the development of the nervous system, which includes the brain and spinal cord.According to the American Psychiatric Association Diagnostic and Statistical Manual of Mental Disorders, Fifth Edition, published in 2013, these conditions generally appear in early childhood, usually before children start school, and ...
A newly identified neurodevelopmental disorder may explain tens of thousands of cases of intellectual disability whose cause was previously unknown. ... a genetic disorder that causes babies to ...
A 2017 study [8] [9] tested all 20,000 genes in about 4,300 families with children with rare developmental difficulties in the UK and Ireland in order to identify if these difficulties had a genetic cause. They found 14 new developmental disorders caused by spontaneous genetic mutations not found in either parent (such as a fault in the CDK13 ...
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