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  2. Knockout mouse - Wikipedia

    en.wikipedia.org/wiki/Knockout_mouse

    There are several thousand different strains of knockout mice. [3] Many mouse models are named after the gene that has been inactivated. For example, the p53 knockout mouse is named after the p53 gene which codes for a protein that normally suppresses the growth of tumours by arresting cell division and/or inducing apoptosis.

  3. International Knockout Mouse Consortium - Wikipedia

    en.wikipedia.org/wiki/International_Knockout...

    The International Knockout Mouse Consortium (IKMC) is a scientific endeavour to produce a collection of mouse embryonic stem cell lines that together lack every gene in the genome, and then to distribute the cells to scientific researchers to create knockout mice to study.

  4. Genetically modified mouse - Wikipedia

    en.wikipedia.org/wiki/Genetically_modified_mouse

    A genetically modified mouse, genetically engineered mouse model (GEMM) [1] or transgenic mouse is a mouse (Mus musculus) that has had its genome altered through the use of genetic engineering techniques. Genetically modified mice are commonly used for research or as animal models of human diseases and are also used for research on genes.

  5. International Mouse Phenotyping Consortium - Wikipedia

    en.wikipedia.org/wiki/International_Mouse_Pheno...

    The International Mouse Phenotyping Consortium (IMPC) is an international scientific endeavour to create and characterize the phenotype of 20,000 knockout mouse strains. [1] [2] [3] Launched in September 2011, [1] the consortium consists of over 15 research institutes across four continents with funding provided by the NIH, European national governments and the partner institutions.

  6. Mouse - Wikipedia

    en.wikipedia.org/wiki/Mouse

    A mouse (pl.: mice) is a small rodent. Characteristically, mice are known to have a pointed snout, small rounded ears, a body-length scaly tail, and a high breeding rate. The best known mouse species is the common house mouse (Mus musculus). Mice are also popular as pets. In some places, certain kinds of field mice are locally common. They are ...

  7. Husband thought wife ‘saw a mouse.’ Her scream was for their ...

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  8. Nc/Nga mice model - Wikipedia

    en.wikipedia.org/wiki/Nc/Nga_mice_model

    Nc/Nga is an inbred mouse model bred in Japan at Nagoya University in 1957. It is used as a human atopic dermatitis model for its biological properties. If kept under so called conventional conditions these mice develop skin lesions clinically and histologically very similar to human atopic dermatitis. The hair of these mice is rougher ...

  9. Knockout rat - Wikipedia

    en.wikipedia.org/wiki/Knockout_rat

    Although published knockouts exist for approximately 60% [13] of mouse genes, a large majority of common human diseases do not have a knockout mouse model. Knockout rat models are an alternative to mice that may enable the creation of new gene disruptions that are unavailable in the mouse. Knockout rat models can also complement existing ...

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