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Chlortalidone, also known as chlorthalidone, is a thiazide-like diuretic drug [1] used to treat high blood pressure, swelling (such as occurs in heart failure, liver failure, and nephrotic syndrome), diabetes insipidus, and renal tubular acidosis.
Antihypertensive agents comprise multiple classes of compounds that are intended to manage hypertension (high blood pressure). Antihypertensive therapy aims to maintain a blood pressure goal of <140/90 mmHg in all patients, as well as to prevent the progression or recurrence of cardiovascular diseases (CVD) in hypertensive patients with established CVD. [2]
Atenolol/chlorthalidone, also known as co-tenidone, is a combination medication used to treat high blood pressure. [2] [3] It is made up of atenolol, a beta-blocker and chlortalidone, a diuretic. [4] It is not recommended as an initial treatment but may be used in those who are taking atenolol and chlortalidone individually. [5] It is taken by ...
Chlorthalidone is the thiazide drug that is most strongly supported by the evidence as providing a mortality benefit; in the ALLHAT study, a chlorthalidone dose of 12.5 mg was used, with titration up to 25 mg for those subjects who did not achieve blood pressure control at 12.5 mg. Chlorthalidone has repeatedly been found to have a stronger ...
Researchers are working to develop a unique anticoagulant (blood thinner) that would bring a lower risk of bleeding than the options currently on the market.
The enormous rough diamond, called vorapaxar, that Merck picked up in the Schering-Plough merger has been cut smaller and smaller during costly late-stage development. The first big setback was a ...
Examples include metolazone, chlorthalidone, and indapamide. [1] References This page was last edited on 4 May 2022, at 02:01 (UTC). Text is available under ...
An anticoagulant, commonly known as a blood thinner, is a chemical substance that prevents or reduces the coagulation of blood, prolonging the clotting time. [1] Some occur naturally in blood-eating animals, such as leeches and mosquitoes, which help keep the bite area unclotted long enough for the animal to obtain blood.