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George Eliava pioneered the use of phages in treating bacterial infections. Phages were discovered to be antibacterial agents and were used in the former Soviet Republic of Georgia (pioneered there by Giorgi Eliava with help from the co-discoverer of bacteriophages, Félix d'Hérelle) during the 1920s and 1930s for treating bacterial infections.
While knowledge was being accumulated regarding the biology of phages and how to use phage cocktails correctly, early uses of phage therapy were often unreliable. [29] Since the early 20th century, research into the development of viable therapeutic antibiotics had also been underway, and by 1942, the antibiotic penicillin G had been ...
Population distribution by country in 1939. This is a list of countries by population in 1939 (including any dependent, occupied or colonized territories for empires), providing an approximate overview of the world population before World War II.
Bacterial resistance to phages puts pressure on the phages to develop stronger effects on the bacteria. The Red Queen hypothesis describes this relationship, as the organisms must constantly adapt and evolve in order to survive. [15] This relationship is important to understand as phages are now being used for more practical and medicinal purposes.
Many of the leaders of the emerging field of molecular biology were alumni of the phage course, which continued to be taught through the 1950s and 1960s. [ 24 ] [ 25 ] In 1995, Millard Susman published a retrospective article on the phage course as it was given over the years (1945 – 1970) both at Cold Spring Harbor (New York) and at the ...
Mycobacteriophage Bxb1 Structure [1]. A mycobacteriophage is a member of a group of bacteriophages known to have mycobacteria as host bacterial species. While originally isolated from the bacterial species Mycobacterium smegmatis and Mycobacterium tuberculosis, [2] the causative agent of tuberculosis, more than 4,200 mycobacteriophage species have since been isolated from various environmental ...
The report lists the quantities of PX used and the number of infected individuals in various locations in China, including Nong'an, Quzhou, Ningbo, Changde, Guangxin, Guangfeng and Yushan. It states that over 26,000 people were infected once or twice, defining PX as "the best bacterial bomb, capable of causing psychological and economic panic ...
In silico comparative genomics and taxonomic analysis have found that crAss-like phages represent a highly abundant and diverse family of viruses. [ 2 ] [ 3 ] CrAss-like phage were predicted to infect bacteria of the Bacteroidota phylum and the prediction was later confirmed when the first crAss-like phage (crAss001) was isolated on a ...