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A BI-RADS classification of 4 or 5 warrants biopsy to further evaluate the offending lesion. [3] Some experts believe that the single BI-RADS 4 classification does not adequately communicate the risk of cancer to doctors and recommend a subclassification scheme: [4] 4A: low suspicion of malignancy, about > 2% to ≤ 10% likelihood of malignancy
The distribution of the lesions could be linked to the clinical evolution [25] Post-mortem autopsies reveal that gray matter demyelination occurs in the motor cortex, cingulate gyrus, cerebellum, thalamus and spinal cord. [26] Cortical lesions have been observed specially in people with SPMS but they also appear in RRMS and clinically isolated ...
Sagittal CT of the lumbar spine showing Baastrup's sign. The salient feature of the disorder is the exuberant osteophytosis that occurs at posterior lumbar spinous processes. Osteophytes are coarse calcifications at the edges of bone that form due to repetitive stress and trauma.
The most common lesions are erythema nodosum, plaques, maculopapular eruptions, subcutaneous nodules, and lupus pernio. Treatment is not required, since the lesions usually resolve spontaneously in two to four weeks. Although it may be disfiguring, cutaneous sarcoidosis rarely causes major problems. [1]
When symptomatic, they can cause pain and myelopathy by intra-spinal bleeding, bony expansion or extra-osseous extension into surround soft tissue or the posterior neural elements. [4] [6] [7] [8] Highly vascular (cavernous type) hemangiomas can produce neurologic deficits without prominent evidence of spinal cord compression. The deficits in ...
The terms "Tarlov cyst" or "sacral perineural cyst" refer to cystic lesions of the spinal meninges with innervation as well as nerve sheath dilatations with subarachnoid communication. While they were once thought to be a histopathological finding, [ 10 ] they can be radiologically confirmed by specialized time lapsed MRI and CT imaging ...
Neurofibromatosis type II (also known as MISME syndrome – multiple inherited schwannomas, meningiomas, and ependymomas) is a genetic condition that may be inherited or may arise spontaneously, and causes benign tumors of the brain, spinal cord, and peripheral nerves. The types of tumors frequently associated with NF2 include vestibular ...
Syringomyelia is a generic term referring to a disorder in which a cyst or cavity forms within the spinal cord. Often, syringomyelia is used as a generic term before an etiology is determined. [3] This cyst, called a syrinx, can expand and elongate over time, destroying the spinal cord.