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In parallel to albuminuria in 1936, discussion on renal lesions observed in patients with diabetes led to the description, by Kimmelstiel and Wilson, of the characteristic nodular fibrotic observed in the diabetic glomeruli (Kimmelstiel and Wilson, 1936b). Kimmelstiel and Wilson introduced the term diabetic nephropathy (DN) to define a clinical ...
Diabetic nephropathy is the leading causes of chronic kidney disease (CKD) and end-stage renal disease (ESRD) globally. The triad of protein leaking into the urine (proteinuria or albuminuria), rising blood pressure with hypertension and then falling renal function is common to many forms of CKD.
Mallet finger is acquired due to injury to the thin extensor tendon that functions to straighten the end (DIP) joint of a finger. [8] Jamming of the finger induces a rupture of the extensor tendon or a broken bone at the tendon's site of attachment. [9] This results in a droopy and crooked appearance of the end joint of the finger, resembling a ...
Acral fibrokeratoma, also known as an acquired digital fibrokeratoma, and acquired periungual fibrokeratoma [1]: 668 is a skin lesion characterized by a pinkish, hyperkeratotic, hornlike projection occurring on a finger, toe, or palm. [2]: 609 [3]: 1817
Different forms of micrographia. Micrographia is an acquired disorder characterized by abnormally small, cramped handwriting. [1] It is commonly associated with neurodegenerative disorders of the basal ganglia, such as in Parkinson's disease, but it has also been ascribed to subcortical focal lesions. [2]
Bizarre parosteal osteochondromatous proliferation (BPOP), also known as Nora's lesion, [4] is a type of non-cancerous bone tumor belonging to the group of cartilage tumors. [ 1 ] [ 2 ] [ 5 ] It is generally seen in the tubular bones of the hands and feet , [ 6 ] where it presents with a rapidly enlarging painless lump in a finger or toe.
A hand imitating an ulnar claw. The metacarpophalangeal joints of the 4th and 5th fingers are extended and the Interphalangeal joints of the same fingers are flexed.. An ulnar claw, also known as claw hand or Spinster’s Claw, is a deformity or an abnormal attitude of the hand that develops due to ulnar nerve damage causing paralysis of the lumbricals.
Dawson's fingers spread along, and from, large periventricular collecting veins, and are attributed to perivenular inflammation. [36] Lesions far away from these veins are known as Steiner's splashes. [30] Sometimes experimental autoimmune encephalomyelitis has been triggered in humans by accident or medical mistake. The damage in these cases ...