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Esketamine, sold under the brand names Spravato (for depression) and Ketanest (for anesthesia) among others, [10] [12] is the S(+) enantiomer of ketamine. [5] [13] It is a dissociative hallucinogen drug used as a general anesthetic and as an antidepressant for treatment of depression.
The researchers on the new study say that infusions of racemic ketamine (which uses two forms of ketamine molecules, in contrast with esketamine’s single form) are cheaper than esketamine and ...
Esketamine is derived from a pediatric anesthetic called ketamine. Through research pioneered at Yale University, it was discovered that the drug seemed to lift heavy, recalcitrant depression ...
Current ketamine treatment is in the form of a nasal spray (in the form of esketamine) or injection. Both require that the patient stays in the clinic to be monitored for around 2 hours. This ...
Ketamine-assisted psychotherapy (KAP) is the use of prescribed doses of ketamine as an adjunct to psychotherapy sessions. KAP shows significant potential in treating mental disorders such as treatment-resistant depression (TRD), anxiety , obsessive–compulsive disorders (OCD), post-traumatic stress disorders (PTSD), and other conditions. [ 1 ]
The more active enantiomer, esketamine (S-ketamine), is also available for medical use under the brand name Ketanest S, [136] while the less active enantiomer, arketamine (R-ketamine), has never been marketed as an enantiopure drug for clinical use. While S-ketamine is more effective as an analgesic and anesthetic through NMDA receptor ...
You may have also heard of ketamine therapy, which uses ketamine, a drug that was originally used as an animal anesthetic, administered in a clinical setting to improve mental health symptoms.
Ketamine: This drug is available as a mixture of both (S)-(+)-ketamine, also known as esketamine, and (R)-(–)-ketamine, also known as arketamine. Pure esketamine is also available. The two have different dissociative and hallucinogenic properties, with esketamine being more potent in isolation as a dissociative. [21]
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