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  2. Evaluation of vesicular-bullous rash - BMJ Best Practice

    bestpractice.bmj.com/topics/en-us/775

    It may indicate a superficial blistering process such as pemphigus, infection-mediated desquamations, and drug eruptions (e.g., toxic epidermal necrolysis). Crust is dried exudate composed of serum, cells, and often bacteria. It may be found overlying erosions in pemphigus. Milia are white keratinous cysts 1 mm to 4 mm in diameter.

  3. Evaluation of maculopapular rash - BMJ Best Practice

    bestpractice.bmj.com/topics/en-us/774

    The term maculopapular rash typically implies an acute and generalized eruption. Morphologic terms. Macule: a flat, circumscribed skin lesion ≤1 cm in greatest diameter. When macules are >1 cm, the appropriate term is patch. Papule: an elevated, circumscribed skin lesion ≤1 cm in diameter. When papules are >1 cm in size, the appropriate ...

  4. Assessment of vesicular-bullous rash - BMJ Best Practice

    bestpractice.bmj.com/topics/en-gb/775

    It may indicate a superficial blistering process such as pemphigus, infection-mediated desquamations, and drug eruptions (e.g., toxic epidermal necrolysis). Crust is dried exudate composed of serum, cells, and often bacteria. It may be found overlying erosions in pemphigus. Milia are white keratinous cysts 1 mm to 4 mm in diameter.

  5. Symptoms, diagnosis and treatment - BMJ Best Practice

    bestpractice.bmj.com/topics/en-gb/3000322

    Ramsay Hunt syndrome typically presents with sudden-onset (<72 hours) unilateral peripheral facial palsy, severe ear/facial pain, and a vesicular ear rash. Other presenting symptoms include vertigo, hearing loss, tinnitus, dry eye, altered taste, and oral lesions. It is caused by reactivation of latent varicella zoster virus (VZV) and spread to ...

  6. Summary. A pustule is a vesicle or bulla containing purulent material. It varies in size and may occur at different levels within the epidermis: subcorneal, intraepidermal, or basement membrane zones. A pustular rash is composed of multiple pustular lesions. The pustules may or may not be sterile and are normally filled with neutrophils.

  7. Symptoms, diagnosis and treatment - BMJ Best Practice

    bestpractice.bmj.com/topics/en-us/23

    Summary. Herpes zoster (also known as shingles) typically presents with pain described as burning or stabbing, followed by a vesicular rash in the affected dermatome; location of symptoms depends on the affected nerve. Diagnosis is primarily based on the typical clinical symptoms, such as dermatomal pain and eruption of grouped vesicles in the ...

  8. Assessment of maculopapular rash - BMJ Best Practice

    bestpractice.bmj.com/topics/en-gb/774

    The term maculopapular rash typically implies an acute and generalised eruption. Morphological terms. Macule: a flat, circumscribed skin lesion ≤1 cm in greatest diameter. When macules are >1 cm, the appropriate term is patch. Papule: an elevated, circumscribed skin lesion ≤1 cm in diameter. When papules are >1 cm in size, the appropriate ...

  9. Assessment of rash in children - BMJ Best Practice

    bestpractice.bmj.com/topics/en-gb/857

    Summary. Rash in children is common. The differential diagnoses are extensive, ranging from self-limiting conditions (e.g., roseola) to life-threatening illnesses such as meningococcal disease. Rash may be the first indication of a potentially serious multi-organ disease or sepsis and should be carefully assessed (see Urgent considerations).

  10. Symptoms, diagnosis and treatment - BMJ Best Practice

    bestpractice.bmj.com/topics/en-us/603

    Varicella-zoster virus (VZV) is an exclusively human virus. The incubation period is about 14 days (range 9 to 21 days). Varicella is characterized by fever, malaise, and a generalized pruritic, vesicular rash. The disease normally presents in childhood and is usually self-limited. Adverse outcomes are more common in immunocompromised people ...

  11. Evaluation of rash in children - BMJ Best Practice

    bestpractice.bmj.com/topics/en-us/857

    Initial considerations in evaluating a rash in children include the morphology, duration, and distribution. Age, sex, family history, medications, known allergies, and exposures are also of primary importance. Generally, rash in the absence of fever or systemic symptoms is not urgent. Macule: a flat area of color change <1 cm in size (e.g ...