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History of aspirin. Aspirin (acetylsalicylic acid), an organic compound that does not occur in nature, was first synthesised in 1899. In 1897, scientists at the drug and dye firm Bayer began investigating acetylated organic compounds as possible new medicines, following the success of acetanilide ten years earlier.
A precursor to aspirin found in the bark of the willow tree (genus Salix) has been used for its health effects for at least 2,400 years. [11] [12] In 1853, chemist Charles Frédéric Gerhardt treated the medicine sodium salicylate with acetyl chloride to produce acetylsalicylic acid for the first time. [13]
Edward Stone was born in Princes Risborough, Buckinghamshire, England, in 1702. His parents were Edward Stone, a gentleman farmer, and his first wife Elizabeth Reynolds. His mother having died, his father took a second wife, Elizabeth Grubb, in 1707; the Grubb family was to play a major role in Stone's life. [ 1]
A new DNA test suggests they might have even self-prescribed an early version of a common modern day painkiller.
Additionally, aspirin induces the formation of NO-radicals in the body, which have been shown in mice to have an independent mechanism of reducing inflammation. This reduces leukocyte adhesion, which is an important step in immune response to infection. There is currently insufficient evidence to show that aspirin helps to fight infection. [17]
The Paleolithic cave art was first discovered in 1868 and depicts bison, deer, and other animals. Scientists have dated the paintings to be between 13,000 to 14,000 years old.
Felix Hoffmann (21 January 1868 – 8 February 1946) was a German chemist notable for re-synthesising diamorphine (independently from C.R. Alder Wright who synthesized it 23 years earlier), which was popularized under the Bayer trade name of "heroin". He is also credited with synthesizing aspirin, though whether he did this under his own ...
The timeline of the evolutionary history of life represents the current scientific theory outlining the major events during the development of life on planet Earth. Dates in this article are consensus estimates based on scientific evidence, mainly fossils. In biology, evolution is any change across successive generations in the heritable ...