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Melioidosis is an infectious disease caused by a gram-negative bacterium called Burkholderia pseudomallei. [1] Most people exposed to B. pseudomallei experience no symptoms; however, those who do experience symptoms have signs and symptoms that range from mild, such as fever and skin changes, to severe with pneumonia, abscesses, and septic shock that could cause death. [1]
Vietnamese tuberculosis refers to certain forms of chronic melioidosis that look clinically very similar to tuberculosis. It is derived from the clinical appearance of the disease in American soldiers returning from the Vietnam War. [citation needed]
Burkholderia is a genus of Pseudomonadota whose pathogenic members include the Burkholderia cepacia complex, which attacks humans and Burkholderia mallei, responsible for glanders, a disease that occurs mostly in horses and related animals; Burkholderia pseudomallei, causative agent of melioidosis; and Burkholderia cepacia, an important pathogen of pulmonary infections in people with cystic ...
Due to the high mortality rate in humans and the small number of organisms required to establish infection, B. mallei is regarded as a potential biological warfare or bioterrorism agent, as is the closely related organism, B. pseudomallei, the causative agent of melioidosis.
Melioidosis (Whitmore's disease) Growing the bacteria in culture mediums Ceftazidime, meropenem, co-trimoxazole: No multiple Meningitis: Lumbar puncture: Antibiotics, antivirals, steroids: No Neisseria meningitidis: Meningococcal disease: Treatment in primary care usually involves intramuscular administration of benzylpenicillin.
Ashdown's medium is a selective culture medium for the isolation and characterisation of Burkholderia pseudomallei (the bacterium that causes melioidosis). Ashdown's medium was first described by LR Ashdown in 1979. [ 1 ]
Burkholderia cepacia complex Scientific classification Domain: Bacteria Phylum: Pseudomonadota Class: Betaproteobacteria Order: Burkholderiales Family: Burkholderiaceae Genus: Burkholderia Species complex: B. cepacia complex Burkholderia cepacia complex (BCC) is a species complex consisting of Burkholderia cepacia and at least 20 different biochemically similar species of Gram-negative ...
Clinical trials have confirmed its efficacy in chronic active [32] and acute otitis media. [33] Travelers' diarrhea, treatment & prophylaxis: Yes: No: No: Clinical trials have confirmed its efficacy as a treatment for travellers' diarrhea. [34] [35] [36] Urinary tract infection: Yes: No: Yes: Clinical trials have confirmed its efficacy in this ...