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Alabama rot, Greenetrack disease, or cutaneous and renal glomerular vasculopathy (CRGV) [1] is an often fatal condition in dogs. It was first identified in the US in the 1980s in greyhounds. [2] [3] The high number of affected dogs at the Greenetrack Racing Park, Alabama, led to the initial pseudonyms of Greenetrack Disease and Alabama Rot. [4]
Acetaminophen (paracetamol, Tylenol) can cause liver damage in dogs. The toxic dose is 150 mg/kg. [174] Ibuprofen * can cause gastrointestinal irritation, stomach ulcers, and kidney damage in dogs. [175] Naproxen (Aleve)* has a long half-life in dogs and can cause gastrointestinal irritation, anemia, melena (digested blood in feces), and vomiting.
What causes kidney disease? The most common causes of CKD are high blood pressure and diabetes , "which damage the small blood vessels and filtering units in the kidneys over time," says Nagata.
Pyelonephritis is inflammation of the kidney, typically due to a bacterial infection. [3] Symptoms most often include fever and flank tenderness. [2] Other symptoms may include nausea, burning with urination, and frequent urination. [2] Complications may include pus around the kidney, sepsis, or kidney failure. [3]
Pyonephrosis (from Greek pyon 'pus' and nephros 'kidney' [1]) is a dangerous kidney infection that is characterized by pus accumulation in the renal collecting system. [2] It is linked to renal collecting system blockage and suppurative renal parenchymal destruction, which result in complete or nearly complete kidney failure. [3]
Symptoms from a lower urinary tract infection include suprapubic pain, painful urination , frequency and urgency of urination despite having an empty bladder. [1] Symptoms of a kidney infection, on the other hand, are more systemic and include fever or flank pain usually in addition to the symptoms of a lower UTI. [10]
When it affects the lower urinary tract it is known as a bladder infection (cystitis) and when it affects the upper urinary tract it is known as a kidney infection (pyelonephritis). [9] Symptoms from a lower urinary tract infection include pain with urination, frequent urination, and feeling the need to urinate despite having an empty bladder ...
In chronic pyelonephritis, patients experience persistent abdominal and flank pain, high fever, decreased appetite, weight loss, urinary tract symptoms and blood in the urine. Chronic pyelonephritis can also lead to scarring of the renal parenchyma caused by recurrent kidney infections. [14]
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