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  2. Congenital heart block - Wikipedia

    en.wikipedia.org/wiki/Congenital_heart_block

    The congenital heart block is a rare disease that affects around 1 child in every 15,000–20,000 births. [3] However, its high mortality (which can be as high as 85% in some severe cases) makes the early diagnosis and intervention very important. [ 1 ]

  3. Neonatal lupus erythematosus - Wikipedia

    en.wikipedia.org/wiki/Neonatal_lupus_erythematosus

    Neonatal lupus erythematosus is an autoimmune disease in an infant born to a mother with anti-Ro/SSA and with or without anti-La/SSB antibodies. [1] [2] The disease most commonly presents with a diffuse/periorbital rash resembling subacute cutaneous lupus erythematosus and can have systemic abnormalities such as complete heart block or hepatosplenomegaly. [3]

  4. Childhood-onset systemic lupus erythematosus - Wikipedia

    en.wikipedia.org/wiki/Childhood-onset_systemic...

    Childhood-onset systemic lupus erythematosus (i.e., cSLE), also termed juvenile-onset systemic lupus erythematosus, juvenile systemic lupus erythematosus, and pediatric systemic lupus erythematosus, is a form of the chronic inflammatory and autoimmune disease, systemic lupus erythematosus (i.e., SLE), that develops in individuals up to 18 years old. [1]

  5. Scientists say they have identified lupus' root cause — and ...

    www.aol.com/news/scientists-identified-lupus...

    The Centers for Disease Control and Prevention estimates that more than 200,000 people in the U.S. have lupus, though the Lupus Foundation of America puts the total much higher: roughly 1.5 ...

  6. Roivant Sciences' lupus drug fails to reduce symptoms in mid ...

    www.aol.com/news/roivant-sciences-lupus-drug...

    The oral drug, brepocitinib, did not meet the primary study goal of reduction in disease activity at week 52 in patients of SLE, in which the immune system that normally helps protect the body ...

  7. Lupus - Wikipedia

    en.wikipedia.org/wiki/Lupus

    The modern period, beginning in 1920, saw major developments in research into the cause and treatment of discoid and systemic lupus. Research conducted in the 1920s and 1930s led to the first detailed pathologic descriptions of lupus and demonstrated how the disease affected the kidney, heart, and lung tissue. [165]

  8. Congenital heart defect - Wikipedia

    en.wikipedia.org/wiki/Congenital_heart_defect

    Supporting people with chronic diseases such as congenital heart disease with emotional problems and mental health is a treatment consideration. [51] Since some people with congenital heart disease have a lower quality of life that is related to their condition, some people may struggle with finding a job, engaging in physical exercise, with ...

  9. Third-degree atrioventricular block - Wikipedia

    en.wikipedia.org/wiki/Third-degree_atrio...

    The cause of congenital third-degree heart block in many patients is unknown. Studies suggest that the prevalence of congenital third-degree heart block is between 1 in 15,000 and 1 in 22,000 live births. [citation needed] Hyperkalemia in those with previous cardiac disease [8] and Lyme disease can also result in third-degree heart block. [9]

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