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C 6 H 4 Br 2: Molar mass: 235.906 g/mol Appearance colorless liquid colorless liquid white solid CAS number [583-53-9] [108-36-1] [106-37-6] Properties Density and phase: 1.9940 g/ml, liquid 1.9523 g/ml, liquid 1.84 g/ml, solid Solubility in water: practically insoluble Other solubilities Soluble in 70 parts ethanol. Soluble in benzene ...
1,3-Dibromobenzene has been used as a starting material in the synthesis of antiviral Lufotrelvir, in human clinical trials for the treatment of COVID-19. [3] The first step is formylation of 1,3-dibromobenzene to 2,6-dibromobenzaldehyde, by lithiation with lithium diisopropylamide in THF , followed by quenching with dimethylformamide .
The three possible arrangements of the nitro groups afford three isomers, 1,2-dinitrobenzene, 1,3-dinitrobenzene, and 1,4-dinitrobenzene. Each isomer has the chemical formula C 6 H 4 N 2 O 4 and a molar mass of about 168.11 g/mol. 1,3-Dinitrobenzene is the most common isomer and it is used in the manufacture of explosives .
1,3-Dibromo-2-hydroxybenzene 3,4-Dibromophenol, 1,2-Dibromo-4-hydroxybenzene 3,5-Dibromophenol, 1,3-Dibromo-5-hydroxybenzene Structural formula: CAS Number: 57383-80-9: 615-58-7: 28165-52-8: 608-33-3: 615-56-5: 626-41-5 PubChem: CID 34264 from PubChem: CID 12005 from PubChem: CID 34177 from PubChem: CID 11847 from PubChem: CID 12003 from ...
1,3-Dinitrobenzene is accessible by nitration of nitrobenzene. The reaction proceeds under acid catalysis using sulfuric acid. The directing effect of the nitro group of nitrobenzene leads to 93% of the product resulting from nitration at the meta-position. The ortho- and para-products occur in only 6% and 1%, respectively. [1]
If the benzene ring contains other substituents, it belongs in Category:Nitrobenzene derivatives Wikimedia Commons has media related to Nitrobenzenes . The main article for this category is Nitrobenzenes .
4-Fluorobromobenzene is synthesized via bromination of fluorobenzene in the presence of a Lewis acid catalyst such as iron(III) bromide or aluminium tribromide. [2]4-Bromofluorobenzene is regarded by the Toxic Substances Control Act as a high production volume chemical, that is, a chemical that 1 million pounds (about 500 tonnes) per year is either produced in or imported to the United States.
This reagent can be used, e.g. in the reaction with carbon dioxide to prepare benzoic acid. [4] Other methods involve palladium-catalyzed coupling reactions , such as the Suzuki reaction . Bromobenzene is used as a precursor in the manufacture of phencyclidine .