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A growing body of research and numerous anecdotal reports link cannabis with several health benefits.
A dried cannabis flower. The short-term effects of cannabis are caused by many chemical compounds in the cannabis plant, including 113 [clarification needed] different cannabinoids, such as tetrahydrocannabinol, and 120 terpenes, [1] which allow its drug to have various psychological and physiological effects on the human body.
The earliest systematic studies of physiological effects of cannabis-derived chemical were conducted in the 1920's (see Fig. The number of publications about marijuana/cannabis). The level or research activity in this area remained relatively low and constant until 1966, when a 10-fold increase in publication activity occurred within 10 years.
Over time, the marijuana gateway hypothesis has been studied more and more. In one published study, the use of marijuana was shown not a reliable gateway cause of illicit drug use. [67] However, social factors and environment influence drug use and abuse, making the gateway effects of cannabis different for those in differing social circumstances.
Organizations and companies operating in cannabis markets have pushed education and marketing of terpenes in their products as a way to differentiate taste and effects of cannabis. [23] The entourage effect , which describes the synergy of cannabinoids, terpenes, and other plant compounds, has also helped further awareness and demand for ...
The time to onset of effects depends strongly on stomach content, but is usually 1 to 2 hours, and may continue for a considerable length of time, whereas the effects of smoking or vaporizing cannabis are almost immediate, lasting a shorter length of time. [10] All of the active constituents enter the body when cannabis is consumed orally.
Rimonabant blocks the CB 1 receptor selectively and has been shown to decrease food intake and regulate body-weight gain. The prevalence of obesity worldwide is increasing dramatically and has a great impact on public health. The lack of efficient and well-tolerated drugs to cure obesity has led to an increased interest in research and ...
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