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  2. Smoker's macrophages - Wikipedia

    en.wikipedia.org/wiki/Smoker's_macrophages

    Smoker's macrophages affect the elastic fibers in the mucus layer of the airways, tightening the lumen and causing asthma. Symptoms of asthma include wheezing, coughing, and chest discomfort. To ameliorate the situation, drugs that either suppress the inflammatory response or relaxes the airway will be administrated, so air can pass through.

  3. If You're Living With Asthma, Here's Every Single Treatment ...

    www.aol.com/youre-living-asthma-heres-every...

    Treat an asthma attack by visiting the hospital. Every year, more than 1.6 million Americans wind up in the emergency room because of an asthma attack, according to the CDC.If your attack is so ...

  4. Asthma-COPD overlap - Wikipedia

    en.wikipedia.org/wiki/Asthma-COPD_overlap

    The major criteria are: a persistent airflow limitation (a ratio of forced expiratory volume in 1 second divided by forced vital capacity of less than 0.7 or below the lower limit of normal), a significant exposure history to tobacco smoke (defined as a greater than 10-pack/year history), or significant exposure to other indoor or outdoor air ...

  5. Airway remodelling - Wikipedia

    en.wikipedia.org/wiki/Airway_remodelling

    Bronchial thermoplasty is the only treatment modality designed to combat a hallmark of airway remodelling; airway smooth muscle hypertrophy. The effects of bronchial thermoplasty on smooth muscle mass are seen up to at least 12 months post-treatment; however, the procedure does not seem to impact other features of airway remodelling. [4]

  6. Pathophysiology of asthma - Wikipedia

    en.wikipedia.org/wiki/Pathophysiology_of_asthma

    The airways narrow and produce excess mucus, making it difficult to breathe. In essence, asthma is the result of an immune response in the bronchial airways. [3] The airways of asthma patients are "hypersensitive" to certain triggers, also known as stimuli (see below).

  7. GSK's asthma drug Nucala meets main goal in study on ... - AOL

    www.aol.com/news/gsks-asthma-drug-nucala-meets...

    Nucala, known also as mepolizumab, was first approved in 2015 for a type of severe asthma in the United States. Its sales grew 18% to 1.7 billion pounds in 2023. It contributed nearly 6% to GSK ...

  8. Anti-asthmatic agent - Wikipedia

    en.wikipedia.org/wiki/Anti-asthmatic_agent

    An anti-asthmatic agent, also known as an anti-asthma drug, refers to a drug that can aid in airway smooth muscle dilation to allow normal breathing during an asthma attack or reduce inflammation on the airway to decrease airway resistance for asthmatic patients, or both. The goal of asthmatic agents is to reduce asthma exacerbation frequencies ...

  9. Reactive airway disease - Wikipedia

    en.wikipedia.org/wiki/Reactive_airway_disease

    Reactive airway disease (RAD) is an informal label that physicians apply to patients with symptoms similar to those of asthma. [1] An exact definition of the condition does not exist. [ 1 ] [ 2 ] Individuals who are typically labeled as having RAD generally have a history of wheezing, coughing, dyspnea , and production of sputum that may or may ...

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