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Escitalopram has not been shown to affect serial reaction time ... side effects when taking SSRIs or after ... patent expiration date from 7 December 2009, to 14 ...
But research conducted by the FDA demonstrates that 90 percent of more than 100 drugs—both prescription and over-the-counter—are perfectly good to use even 15 years after the expiration date.
The labeled expiration date is a manufacturer's promise for a time until which the drug will have full efficacy and be safe as manufactured. [4] The labeled expiration date is not an indication of when a drug has become ineffective or unsafe to use. [4] Many drugs are effective for years after their expiration dates. [4]
The SSRIs also have less affinity for α 1, α 2, H 1 and muscarinic receptors, which might explain the differences of adverse events between TCAs and SSRIs. [6] Although SSRIs arrive rapidly to the brain after administration and the effects on 5-HT re-uptake can be measured instantly, it takes about 2–4 weeks to get therapeutic effects. [16]
What are SSRIs and what does SSRI stand for? SSRIs are a group of antidepressants known as selective serotonin reuptake inhibitors that work to prevent the brain from reabsorbing serotonin, a key ...
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Antidepressants with a lower half-life, such as paroxetine, duloxetine, and venlafaxine, have been implicated in higher incidences of withdrawal symptoms and more severe withdrawal symptoms. [25] With SSRIs, duration of treatment does not appear associated with the severity of withdrawal symptoms. [24]
Some people may need antidepressants for a relatively short period (like while grieving the loss of a loved one), or they might need medication long-term, if the depression is chronic.