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Prostate-specific antigen (PSA), also known as gamma-seminoprotein or kallikrein-3 (KLK3), P-30 antigen, is a glycoprotein enzyme encoded in humans by the KLK3 gene.PSA is a member of the kallikrein-related peptidase family and is secreted by the epithelial cells of the prostate gland in men and the paraurethral glands in women.
B1: the tumor can be felt and it does not occupy a whole lobe; B2: the tumor can be felt and it occupies a whole lobe or both lobes; C: the tumor has extended through the capsule C1: the tumor has extended through the capsule but does not involve the seminal vesicles; C2: the tumor involves the seminal vesicles; D: the tumor has spread to other ...
The rad is a unit of radiation absorbed dose, defined as 1 rad = 0.01 Gy = 0.01 J/kg. [1] It was originally defined in CGS units in 1953 as the dose causing 100 ergs of energy to be absorbed by one gram of matter.
After analyzing the data, if the p-value is less than α, that is taken to mean that the observed data is sufficiently inconsistent with the null hypothesis for the null hypothesis to be rejected. However, that does not prove that the null hypothesis is false. The p-value does not, in itself, establish probabilities of hypotheses. Rather, it is ...
The term significance does not imply importance here, and the term statistical significance is not the same as research significance, theoretical significance, or practical significance. [ 1 ] [ 2 ] [ 18 ] [ 19 ] For example, the term clinical significance refers to the practical importance of a treatment effect.
The weighted harmonic mean of p-values , …, is defined as = = = /, where , …, are weights that must sum to one, i.e. = =.Equal weights may be chosen, in which case = /.. In general, interpreting the HMP directly as a p-value is anti-conservative, meaning that the false positive rate is higher than expected.
Because of the commutative property of multiplication, reversing expressions does not change the result; for example, 50% of 20 is 10, and 20% of 50 is 10. Variants of the percentage calculation The calculation of percentages is carried out and taught in different ways depending on the prerequisites and requirements.
4 January – A review indicates digital rectal examination (DRE) is an outdated routine medical practice, with a lower cancer detection rate compared to prostate-specific antigen (PSA) testing and no benefit from combining DRE and PSA. [4] [5] 5 January
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