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4,7-Dichloroquinoline was first reported in a patent filed by IG Farben in 1937. [2] However, its synthesis was not investigated in detail until chloroquine was developed as an antimalarial drug. [ 3 ] : 130–132 A route to the intermediate starting from 3-chloroaniline was developed by chemists at Winthrop Chemical Co .
[1] [4] Chloroquine is a member of the drug class 4-aminoquinoline. [1] As an antimalarial, it works against the asexual form of the malaria parasite in the stage of its life cycle within the red blood cell. [1] How it works in rheumatoid arthritis and lupus erythematosus is unclear. [1] Chloroquine was discovered in 1934 by Hans Andersag.
2-Propenoic acid, polymer with sodium phosphinate (1:1) No record 66019-18-9: 2-propenoic acid, telomer with sodium hydrogen sulfite: No record 107-19-7: 2-Propyn-1-ol / propargyl alcohol: No record 51229-78-8: 3,5,7-Triaza-1-azoniatricyclo[3.3.1.13,7]decane, 1-(3-chloro-2-propenyl)-chloride: Clean pressed powder 115-19-5: 3-methyl-1-butyn-3-ol ...
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[3] [4] Although all risk cannot be excluded, it remains a treatment for rheumatic disease during pregnancy. [5] Hydroxychloroquine is in the antimalarial and 4-aminoquinoline families of medication. [3] Hydroxychloroquine was approved for medical use in the United States in 1955. [3] It is on the World Health Organization's List of Essential ...
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