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  2. Hardy–Weinberg principle - Wikipedia

    en.wikipedia.org/wiki/HardyWeinberg_principle

    The HardyWeinberg principle can also be used to estimate the frequency of carriers of an autosomal recessive condition in a population based on the frequency of suffers. Let us assume an estimated 1 2500 {\displaystyle \textstyle {\frac {1}{2500}}} babies are born with cystic fibrosis , this is about the frequency of homozygous individuals ...

  3. Wahlund effect - Wikipedia

    en.wikipedia.org/wiki/Wahlund_effect

    This point always has a lower heterozygosity (y value) than the corresponding (in allele frequency p) Hardy-Weinberg equilibrium. In population genetics, the Wahlund effect is a reduction of heterozygosity (that is when an organism has two different alleles at a locus) in a population caused by subpopulation structure.

  4. Genetic equilibrium - Wikipedia

    en.wikipedia.org/wiki/Genetic_equilibrium

    Genetic equilibrium itself, whether Hardy-Weinberg or otherwise, provides the groundwork for a number of applications, in including population genetics, conservation and evolutionary biology. With the rapid increase in whole genome sequences available as well as the proliferation of anonymous markers, models have been used to extend the initial ...

  5. Wilhelm Weinberg - Wikipedia

    en.wikipedia.org/wiki/Wilhelm_Weinberg

    Wilhelm Weinberg (25 December 1862 – 27 November 1937) was a German obstetrician-gynecologist, practicing in Stuttgart, who in a 1908 paper, published in German in Jahresheft des Vereins für vaterländische Naturkunde in Württemberg (The Annals of the Society of National Natural History in Württemberg), expressed the concept that would later come to be known as the HardyWeinberg principle.

  6. Additive disequilibrium and z statistic - Wikipedia

    en.wikipedia.org/wiki/Additive_Disequilibrium...

    Similarly, we can also test for Hardy Weinberg Equilibrium using the z-statistic, which uses information from the estimate of additive disequilibrium to determine significance. When using the z- statistic, however, the goal is to transform the statistic in a way such that asymptotically , it has a standard normal distribution .

  7. Hardy–Weinberg - Wikipedia

    en.wikipedia.org/?title=HardyWeinberg&redirect=no

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  8. Robert Weinberg (biologist) - Wikipedia

    en.wikipedia.org/wiki/Robert_Weinberg_(biologist)

    Robert Weinberg is also affiliated with the Broad Institute and is a founding member of the Whitehead Institute for Biomedical Research. [5] Weinberg and Eric Lander, a colleague at M.I.T., are co-founders of Verastem, a biopharmaceutical company focused on discovering and developing drugs to treat cancer by targeting cancer stem cells. [6]

  9. Electroweak interaction - Wikipedia

    en.wikipedia.org/wiki/Electroweak_interaction

    Weinberg's weak mixing angle θ W, and relation between coupling constants g, g′, and e. Adapted from Lee (1981). [7] The pattern of weak isospin, T 3, and weak hypercharge, Y W, of the known elementary particles, showing the electric charge, Q, along the weak mixing angle. The neutral Higgs field (circled) breaks the electroweak symmetry and ...