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The collecting duct system of the kidney consists of a series of tubules and ducts that physically connect nephrons to a minor calyx or directly to the renal pelvis.The collecting duct participates in electrolyte and fluid balance through reabsorption and excretion, processes regulated by the hormones aldosterone and vasopressin (antidiuretic hormone).
The proximal tubule is the segment of the nephron in kidneys which begins from the renal pole of the Bowman's capsule to the beginning of loop of Henle.At this location, the glomerular parietal epithelial cells (PECs) lining bowman’s capsule abruptly transition to proximal tubule epithelial cells (PTECs).
Renal corpuscle showing glomerulus and glomerular capillaries Figure 2: (a) Diagram of the juxtaglomerular apparatus: it has specialized cells working as a unit which monitor the sodiujuxtaglomerular apparatus: it has three types of specm content of the fluid in the distal convoluted tubule (not labelled - it is the tubule on the left) and adjust the glomerular filtration rate and the rate of ...
Reabsorption of HCO 3 − occurs in the proximal tubule, in the ascending limb of the loop of Henle, and to a lesser extent in the distal convoluted tubule of the nephron. H + secretion is carried out mainly through Na + /H + exchangers in the tubules of the nephron. [150] The collecting ducts are involved in the energy-dependent secretion of H ...
As a result, the filtrate leaving the Bowman's capsule is very similar to blood plasma (filtrate or glomerular filtrate is composed of blood plasma minus plasma protein i.e. it contains all the components of blood plasma except the proteins) in composition as it passes into the proximal convoluted tubule.
Convoluted tubule is the compound of a metanephridium which is wrapped with capillaries. It is highly coiled so as to increase surface area for more effective reabsorption, which occurs in this part of the metanephridium. The distal tubule of the mammalian kidney is the portion of the nephron located between the macula densa region and the ...
The macula densa is a collection of densely packed epithelial cells at the junction of the thick ascending limb (TAL) and distal convoluted tubule (DCT). As the TAL ascends through the renal cortex, it encounters its own glomerulus , bringing the macula densa to rest at the angle between the afferent and efferent arterioles .
proximal tubule loop of Henle Distal convoluted tubule Collecting duct system; S1 S2 S3 descending limb: thin ascending limb: thick ascending limb: connecting tubule: initial collecting tubule cortical collecting ducts medullary collecting ducts Na + 142 [1] 142 [1] 100 [1] 70 [1] 40 [1]